Title of dissertation: IMPACT OF STOCHASTICITY ON GENE REGULATION NETWORKS Xin Fang Doctor of Philosophy, 2007 Dissertation directed by: Professor Evanghelos Zafiriou Department of Chemical and Biomolecular Engineering We studied the impact of stochasticity on gene regulation networks, using the cell-to-cell communication mechanism in Escherichia coli as an example. First we explored signal med...

objective(s): the aim of this study was to investigate the methylation status and mrna expression levels of p15, death-associated protein kinase (dapk), and suppressor of cytokine signaling-1 (socs1) genes in multiple myeloma (mm). materials and methods: the bone marrow samples of 54 mm patients were collected and the methylation status of the p15, dapk, and socs1 gene promoter regions was dete...

conclusions some results of the correlation coefficients are not the same with visualization. the reason may be due to the small number of data. materials and methods in the foundation-application study, we constructed two-way gene networks using nonparametric methods, such as spearman’s rank correlation coefficient and blomqvist’s measure, and compared them with pearson’s correlation coefficie...

The ability to form different types of biofilm enables bacteria to survive in a harsh or toxic environment. Different structures of biofilms are related to different surfaces and environment of bacterial growth. The aim of this study was analysis of the biofilm formation of 115 clinical uropathogenic Escherichia coli strains under different growth conditions: surface for biofilm formation, medi...

Escherichia coli O157:H7 is a food-borne pathogen causing hemorrhagic colitis and hemolytic-uremic syndrome, especially in children. The main virulence factor responsible for the more serious disease is the Shiga toxin 2 (Stx2), which is released in the gut after oral ingestion of the organism. Although it is accepted that the amount of Stx2 produced by E. coli O157:H7 in the gut is critical fo...

1. Abstract 2. Introduction 3. Adult neural stem cells and neurogenesis 3.1. Hippocampal stem cells 3.2. Subventricular zone (SVZ) and olfactory bulb stem cells 3.3. Progenitors derived from non-neurogenic regions 3.4. Adult neural stem cell engraftment in vivo 3.4.1. Hippocampal derived neural stem cells 3.4.2. SVZ derived neural stem cells 3.4.3. Spinal cord progenitors 3.4.4. Cortical derive...