Adults of Schistosoma edwardiense Thurston, 1964, were recovered from Hippopotamus amphibius in the Kruger National Park. Small round to oval Schistosoma margrebowiei-like eggs, presumed to be those of S. edwardiense, were found fairly frequently in the faeces of infected hippopotami together with a few Schistosoma haematobium-like eggs the identity of which remains uncertain. Biomphalaria sp.,...

BACKGROUND Stunted development and reduced fecundity of Schistosoma parasites in immunodeficient mice and the impaired ability of human immunodeficiency virus 1 (HIV-1)-infected humans to excrete schistosome eggs have been described. This study explores the effect that HIV-1-associated immunodeficiency has on the excretion of schistosome eggs in a large cohort of coinfected individuals. METHO...

background: in view of the massive rural-to-urban migration in nigeria, investigations on transmission of urinary schistosomiasis were carried out in ur-ban and semi-urban communities in nike lake area of enugu state, nigeria. methods : urine samples of school children were tested for micro-haematuria using reagent strips followed by microscopic examination for schistosoma haematobium eggs. wat...

One of the major lessons we learned from the radiation-attenuated cercariae vaccine studies is that protective immunity against schistosomiasis is dependent on the induction of T helper (Th)1-/Th2-related immune responses. Since most schistosome larval and adult-worm-derived molecules used for vaccination uniformly induce a polarized Th1 response, it was essential to include a type 2 immune res...

Schistosoma is a name derived from the Greek words (schisto means split and soma means body), because the body of male appears splitting longitudinally to produce a canal. Schistosoma is one of a trematoda but with separate sexes. Male is broader than the female and its lateral borders are curved ventrally forming long groove called gynaecophoric canal in which the female is held[1]. Schistosom...

We have detected species, strain, and sex-specific genetic markers for the genus Schistosoma by Southern blot analysis of its DNA using cloned DNA segments of the Schistosoma mansoni ribosomal gene as probes. Restriction analysis of DNA from eight different strains of S. mansoni, from Africa and the Caribbean, revealed that the predominant or major DNA fragment containing the ribosomal gene uni...

Screening for Schistosoma haematobium infection and its possible morbidity was carried out in 257 adult participants in Eggua community, Ogun State, Nigeria. Parasitological assessment for the presence of ova of S. haematobium in urine and abdominopelvic ultrasonographic examination for bladder and secondary kidney pathology were carried out. S. haematobium prevalence of 25.68% (66/257) was rec...

Chronic infection with the blood fluke, Schistosoma haematobium, is associated with squamous cell carcinoma of the bladder. Previously, it has been shown that soluble extracts of mixed sex adult S. haematobium worms (SWAP) are tumourigenic, both in vitro and in vivo. In addition, oestrogen-related molecules in SWAP of S. haematobium down-regulate oestrogen receptors (ERs) alpha and beta in oest...