Invasive ductal carcinoma (IDC) of the breast is currently graded according to the Nottingham modification of the Scarff-Bloom-Richardson system (SBR). This system involves subjective evaluation of 3 morphologic features: tubule formation, nuclear pleomorphism, and mitosis. Our recently proposed semi-automated Nuclear and Proliferation Index [N+P] grading system for IDC has demonstrated agreeme...

When studying the colloidal stability of an immunolatex formed by F(ab')2 protein fragments and a polystyrenepolychloromethylstyrene copolymer, striking results were obtained. After the expected particle aggregation induced by an increase in the electrolyte concentration (KBr), subsequent restabilization occurred when this electrolyte concentration was increased even more. This non-DLVO behavio...

A major challenge in functional neuroimaging is to cope with individual variability in cortical structure and function. Most analyses of cortical function compensate for variability using affine or low-dimensional nonlinear volume-based registration (VBR) of individual subjects to an atlas, which does not explicitly take into account the geometry of cortical convolutions. A promising alternativ...

Intestinal adaptation following small bowel resection (SBR) is associated with greater rates of enterocyte apoptosis by unknown mechanism(s). Because postresection adaptation is associated with increased translocation of luminal bacteria, we sought to characterize the role for the extrinsic, death receptor pathway for the activation of enterocyte apoptosis after massive SBR. We first performed ...

The planthopper Pentastiridius leporinus (Hemiptera: Cixiidae) is the major vector of a nonculturable plant-pathogenic gamma-3 proteobacterium associated with a disease of sugar beet called syndrome "basses richesses" (SBR). The bacterium, here called SBR bacterium, belongs to the Arsenophonous clade, which includes mostly insect-associated facultative symbionts. Assays using field-collected pl...

Previous work in our group has demonstrated that mouse salivary gland has the highest concentration of salivary-derived VEGF protein compared with other organs and is essential for normal palatal mucosal wound healing. We hypothesize that salivary VEGF plays an important role in maintaining the integrity of the gastrointestinal mucosa following small bowel resection (SBR). Thirty-five 8- to 10-...

SBR does not depend on the measurement duration, whereas SNR increases with the measurement duration and SBR. These are well known results and do not need further discussion (1-2). However, these simple expressions also show an interesting connection between signal count rate (s) and background count rate (b) illustrated in Fig. S6. Fig. S6 shows curves of constant SNR at a given SBR, as a func...

The Search-Browse-Repeat (SBR) mode of Web usage is becoming increasingly important as the size of the Web increases and the coverage of search engines expands. However, Web browsers do little to support SBR, with consequences for search success rates. We characterise the main features of SBR, suggest criteria that would help alleviate the problems associated with it, and outline a prototype br...

The literature on polymer latex film formation has grown enormously in recent times--driven by the need to find alternatives for solvent-based systems with their adverse environmental impacts. Although greater insight has been shown by the use of modern instrumental techniques such as small angle neutron scattering, direct non-radiative energy transfer and atomic force microscopy, the actual me...