peripheral neuroepitbelioma (pn) is a rare highly malignant tumor, classified in the group of small round cell tumors. we report eight cases of pn, based on histologic appearance and immunohistochemical staining for neuron-specific enolase (nse). electron microscopy was also performed in three cases. the tumors exhibited rapid local growth, leading to limb amputation in five cases. histological...

Sarcomas represent a clinically and biologically diverse group of malignant connective tissue tumors. Despite aggressive conventional therapy, a large proportion of sarcoma patients experience disease recurrence which will ultimately result in mortality. The presence of a unique population of cells, referred to as cancer stem cells (CSCs), have been proposed to be responsible for refractory res...

Background: Ewing's sarcoma/Primitive neuroectodermal tumor (PNET) is a group of tumors with small round cells that originate from nerve stem cells. They are generally more common in children and often occur in the soft or bony tissues of the limbs, trunk, head, and neck. Ewing's sarcoma is a rare disease in the kidney and its tumor thrombosis into Inferior Vena Cava (IVC) is assumed as a very ...

Background & Objective: Soft tissue sarcomas (STS) constitute an uncommon and heterogeneous group of tumors of mesenchymal origin and various cytogenetic abnormalities ranging from distinct genomic rearrangements, such as chromosomal translocations and amplifications, to more intricate rearrangements involving multiple chromosomes. Fluorescence in situ...

background:   although the majority of soft tissue masses are benign, it is important to consider malignancy in differential diagnoses. because most soft tissue sarcomas present as a painless mass, clinicians must watch for signs suggestive of malignancy, including large size, rapid growth, and site deep into the deep fascia.the purpose of this study was to determine the relative prevalence acc...

Different preparations obtained from cultures of Serratia marcescens and Strepto coccus pyogenes were tested in seven spontaneous, induced, and transplanted tumors of mice, and Rous sarcoma in chicks. The toxins were found to be effective against Krebs-2 carcinoma causing regression of well established tumors. They were found to be ineffective against Sarcoma 180, Gardner's Lymphosarcoma 6C3HED...

Periductal stromal sarcoma (PSS) is a an extremely rare low-grade malignant neoplasm arising from breast periductal stroma. It usually occurs in peri and post-menopausal women. Herein, we report case of 14 year girl, known recurrent Rhabdomyosarcoma (RMS) presenting with breast. To the best our knowledge, this first its kind to be reported literature. A 14year Recurrent Pleomorphic retroperiton...

Aim: This study aimed to evaluate the incidence, surgical management, histologic and anatomic distribution of patients who operated in a tertiary orthopedic oncology center with diagnosing primary bone tumors radius.
 
 Material Methods: A total 96 ( 37 female, 59 male ) presented our department period 17 years (2003-2020) diagnosis radius were analyzed. The assessed according age, ge...

Tumors of peripheral nerve are largely neuroectodermal in nature and derived from 2 elements of nerve, Schwann or perineurial cells. In contrast, mesenchymal tumors affecting peripheral nerve are rare and are derived mainly from epineurial connective tissue. The spectrum of the latter is broad and includes lipoma, vascular neoplasms, hematopoietic tumors, and even meningioma. Of malignant perip...

Background. The origin of Ewing's sarcoma in a periosteal location is rare and not clearly documented. Other malignant bone tumors appear to have a somewhat better prognosis when confined between periosteum and bone. Is it the same for periosteal Ewing's sarcoma?Methods. We describe two new cases and comprehensively review the literature consisting of 18 documented cases since the condition was...