BACKGROUND As a potential new treatment for overactive bladder (OAB), we investigated the feasibility of non-invasively activating multiple nerve targets in the lower leg. METHODS In healthy participants, surface electrical stimulation (frequency = 20 Hz, pulse width = 200 μs) was used to target the tibial nerve, saphenous nerve, medial plantar nerve, and lateral plantar nerve. At each locati...

The authors report a case of an angioleiomyoma at the anteromedial side of the knee mimicking a neurinoma of the infrapatellar branch of the saphenous nerve. Angioleiomyomas are benign soft tissue tumors with a predilection for the lower extremities in middle-aged females. Paroxysmal pain is triggered by pressure, cold and hormonal changes. Simple excision is usually curative.

In a previous paper' evidence has been offered that not only the intra-medullary spike but also an early component of the following negative potential (labelled Nia) is of presynaptic origin. N1a was attributed to activity in afferent terminals. The present note deals with the site of origin FIG. 1. Cat 11-11-54. Stimulus to internal saphenous nerve. All upper traces from point 1 on the ipsilat...

BACKGROUND The pes anserine bursa lies beneath the pes anserine tendon, which is the insertional tendon of the sartorius, gracilis, and semitendinosus muscles on the medial side of the tibia, but it can lie in different sites in the medial knee. Accurate diagnosis of the position of the bursa is critical for diagnostic and therapeutic goals. The aim of this study was to evaluate sonoanatomic va...

Static contraction of skeletal muscle elicits a reflex increase in cardiovascular function. Likewise, noxious stimuli activate somatic nociceptors eliciting a reflex increase in cardiovascular function. On the basis of recent work involving spinothalamic cells in the dorsal horn, we hypothesized that the dorsal horn cells involved in the aforementioned reflexes would be sensitized by applying c...

BACKGROUND If a transverse incision can be safely used for total knee arthroplasty (TKA), decreases in scar formation, reduced injury of the infrapatellar branch of the saphenous nerve and improved kneeling motion will be observed. METHODS We evaluated 95 patients (101 knees) on whom primary TKA was performed with follow-up of more than 2 years. A longitudinal incision was used for the first ...

The effect of warming on adrenergic neurotransmission was examined in canine cutaneous veins. Isometric tension was recorded from rings of saphenous veins of the dog in organ chambers filled with physiological salt solution. During contractions caused by potassium or prostaglandin F2 alpha, warming from 37 to 41 degrees C caused an augmentation. During contractions caused by stimulation of the ...

Adenosine and the adenine nucleotides caused a greater relaxation of strips of canine saphenous vein and tibial artery when they had been contracted by nerve stimulation than by exogenous norepinephrine. An infusion of adenosine into the dogs' lateral saphenous vein, perfused at constant flow, caused a greater relaxation of this vein when constricted by electrical stimulation of the lumbar symp...

Recently, several novel approaches to the treatment of migraine have been advanced, including selective 5-hydroxytryptamine (or serotonin) 1B/1D (5-HT(1B/1D)) receptor agonists such as sumatriptan and 5-HT(1F) receptor agonists such as LY344864. Many 5-HT(1B/1D) receptor agonists have been identified based on their ability to produce cerebral vascular contraction, whereas LY344864 was identifie...

The long saphenous vein runs constantly in a deep plane of the hypodermis, lying directly above the muscular fascia (Figure 1). It is covered for its full length by a connective lamina that descends from the inguinal ligament to the ankle in the hypodermis of the medial thigh and leg. This lamina, which is formed by the interlacing of the hypodermal connective sheets, until now has been only pa...