furin is a ca 2+ -dependent serine protease which cleaves proprotein substrates at the arg-xaa-(lys/arg)-arg    site to generate biologically active proteins. furin’s critical role in many cellular events associated with health disorders such as hiv, sars, anthrax, and influenza as well as cancer has made inhibitors of this enzyme as therapeutic targets. to this date, the most potent inhibitor ...

Proteins and peptides are attractive chemical building blocks to encapsulate protect active substances thanks their biocompatibility, biodegradability, low immunogenicity, added functionality compared synthetic polymers. This review provides a comprehensive overview of micro- nanocapsules predominantly made proteins—both natural artificially produced—and peptides, detailing different fabricatio...

background: the aim of the present study was to induce salivation in haemaphysalis longicornis to increase saliva production and to characterize the collection of proteins present in the collected saliva using on-chip-electrophoresis. methods: saliva of adult female engorged h. longicornis was collected by treatment with 0.2% dopamine hydrochlo­ride. all protein samples were characterized by sd...

abstract background antibiotic resistance makes antimicrobial peptides (amps) agents an alternative for treatment of pathogenic diseases. they are isolated from various animals invertebrates, vertebrates and plants. the present study shows the electrophoretic pattern of protein and peptides from vicia faba seed and reports our first attempt to study the antibacterial activity of vicia faba seed...

The intrinsic pathway of apoptosis is regulated by the Bcl-2 family proteins. Inhibition anti-apoptotic members represents a strategy to induce apoptotic cell death in cancer cells. We have measured membrane binding properties series peptides, including modified α/β-peptides, designed exhibit enhanced permeability allow entry and improved access for engagement members. peptide cargo based on pr...