Unlike cancers of related exocrine tissues such as the mammary and prostate gland, diagnosis and treatment of aggressive salivary gland malignancies have not markedly advanced in decades. Effective clinical management of malignant salivary gland cancers is undercut by our limited knowledge concerning the key molecular signals that underpin the etiopathogenesis of this rare and heterogeneous hea...

background: rhipicephalus ( boophilus ) annulatus tick is one of the most important ectoparasite of cattle. re­cently, several laboratories in the world have been concentrated on immunizing cattle against tick using various types of tissue extracts of ticks. the aim of this study was to evaluate the effect of immunization of cattle with tick salivary gland extract on biological parameters of ti...

Purpose: Radiography, Sailography, Scintigraphy, Computerized Tomography, MRI and Ultrasonography are the available diagnostic aids to diagnose salivary gland lesions. All the diagnostic aids have their own limitations in the diagnosis of salivary gland diseases. The advantage of ultrasonography in the diagnosis of salivary gland enlargements is its ease to use, less expensive, less time consum...

by increasing number of vessels. salivary gland tumors are uncommon and their overall incidence is about 3 per 100000 per year. salivary gland hemangioma makes up 1 % of all salivary gland tumors. trismus resulting from parotid hemangioma is so rare. the patient was a 6-month-old boy with a huge lesion in his right parotid who referred to shahid sadoughi hospital of yazd, iran. the lesion appea...

Salivary glands are exocrine that secrete saliva, which plays an important role in the maintenance of oral health. Few reports exist on contralateral salivary gland is not directly affected when one by sialolithiasis, radiation therapy, or a tumor. In present study, we investigated changes submandibular mice following excision unilateral gland. Outcomes this study showed and sublingual resectio...

Significant increase in the salivary gland weight was observed after exposure to single therapeutic dose of 3.7 MBq of 131I in mice. Pre-supplementation of antioxidants, O. sanctum leaf extract, turmeric extract and vitamin E for 15 days before 131I exposure demonstrated significant reduction in the salivary gland weight. No major histopathological changes were observed in the salivary gland of...

BACKGROUND Locoregionally advanced salivary gland malignancies have a poor prognosis despite aggressive therapy. Herein we report our experience in treating high-risk salivary gland malignancies with concurrent chemoradiotherapy (CRT). METHODS Medical records of 15 patients with salivary gland malignancies treated with CRT at our institution between 1997 and 2010 were analyzed. RESULTS All ...

The human kallikrein 5 protein (hK5) is expressed in many normal tissues, most notably in skin, breast, salivary gland and esophagus. It has also been shown to be a potential biomarker for breast, ovarian and testicular cancer. Human kallikrein 3 (hK3; prostate-specific antigen) is the most useful marker for adenocarcinoma of the prostate gland. The aim of this study was to determine whether hK...

OBJECTIVE The commonly associated aetiology of salivary gland inflammation and salivary hypofunction has led to the widely held belief that inflammation causes salivary gland hypofunction. Indeed, our own recent study seemed to support this contention. Here, we tested the hypothesis that, in an acute duct ligation model, eliminating inflammation the submandibular gland would recover normal func...

Salivary gland hypofunction, also known as xerostomia, occurs as a result of radiation therapy for head cancer, Sjögren's syndrome or aging, and can cause a variety of critical oral health issues, including dental decay, bacterial infection, mastication dysfunction, swallowing dysfunction and reduced quality of life. Here we demonstrate the full functional regeneration of a salivary gland that ...