We previously investigated the utility of μ-oxo N,N'- bis(salicylidene)ethylenediamine iron (Fe(Salen)) nanoparticles as a new anti-cancer agent for magnet-guided delivery with anti-cancer activity. Fe(Salen) nanoparticles should rapidly heat up in an alternating magnetic field (AMF), and we hypothesized that these single-drug nanoparticles would be effective for combined hyperthermia-chemother...

Two hydroxo-bridged complexes, {[Mn(III)(3-CH(3)O)salen](2)[Cr(III)(salen)(OH)(2)]}ClO(4)·6H(2)O (1) and {[Mn(III)(5-CH(3))salen](2)(OH)}ClO(4)·3H(2)O (2) [salen = N,N'-ethylenebis(salicylideneiminato) dianion], have been synthesized by the hydrolysis of the corresponding Mn(III)(Schiff-Bases) derivatives and [Cr(salen)(H(2)O)(2)]Cl precursors. X-Ray structure characterization reveals the discr...

The five-coordinate compound, Salen((t)Bu)Al(Ac), prepared in situ from Salen((t)Bu)AlBr and NH4Ac, forms Lewis acid-base adducts in aqueous solution with the G-type nerve agents, Sarin and Soman, and the VX hydrolysis product, ethylmethylphosphonate (EMPA). The resulting compounds, [Salen((t)Bu)Al(NA)](+)[Ac] (-) (with NA = Sarin, Soman, and EMPA) are sufficiently stable to be identified by ES...

The new [Co(Salen)(PBu3)2]ClO4, [Co(Salen)(PBu3)2]BF4, [Co(Salpn)(PBu3)2]ClO4 and [Co(Salen)(PMe2Ph)2]ClO4 ( where salen = bis(salisylaldehyde)ethylenediimine)) complexes were synthesiszed and chracterized by IR, UV-Vis, 1H NMR spectroscopy and elemental analysis. The IR and 1H NMR spectra cofirmed that the synthesised complexes contain Schiff base ligand, phosphane and conter ion and the eleme...

We have observed that the superoxide anion reacts with VO(salen), but not with VO(saldpt), where H2(salen) and H2(saldpt) are Schiff base ligands derived from salicylaldehyde and ethylenediamine or dipropylenetriamine, respectively. Based on the electrochemical, ESR, and UV spectroscopic studies of the reaction mixture, it was concluded that the superox­ ide anion reacts with VO(salen) to oxidi...

The construction of novel (macrocyclic) multinuclear Co(III)salen catalysts is reported. Olefin metathesis has been used as a key construction tool for the multimetallic structures starting from versatile allyl-substituted salen scaffolds. The Co(III) complexes were tested in the hydrolytic kinetic resolution of (rac)-1,2-epoxyhexane and epoxide ring opening reactions using methanol as the nucl...

Anion exchange of BF(4)(-) occurs by stirring a cobalt(III) complex of salen-type ligand tethered by four quaternary ammonium BF(4)(-) salts over a slurry of NaX in CH(2)Cl(2), affording a complex containing four X's per cobalt (X = 2,4,5-trichlorophenolate, 6; X = 4-nitrophenolate, 10; X = 2,4-dichlorophenolate, 12). The (1)H and (13)C NMR spectra are in agreement with an unusual imine uncoord...

By the reaction of chiral Mn(III) Schiff-base complexes with the dicyanoruthenate building block, [Ru(salen)(CN)2](-) (salen(2-) = N,N'-ethylenebis(salicylideneimine) dianion), two couples of enantiomerically pure chiral cyano-bridged heterobimetallic one-dimensional (1D) chain complexes, [Mn((R,R)-salcy)Ru(salen)(CN)2]n (1-(RR)) and [Mn((S,S)-salcy)Ru(salen)(CN)2]n (1-(SS)) (Salcy = N,N'-(1,2-...

This study deals with the synthesis and evaluation of salen based derivatives as fire retardants in thermoplastic polyurethane. Salens, hydroxysalens and their first row transition metal complexes (salen-M) were synthesized (Copper, Manganese, Nickel and Zinc). They were then incorporated in thermoplastic polyurethane (TPU) with a loading as low as 10:1 weight ratio. The thermal stability as we...

Hybrid quantum mechanics/molecular mechanics (QM/MM) methods were employed to study electronic effects of 5,5'-substituents on the enantioselectivity of (salen)Mn catalysts. Correlations obtained from the QM/MM calculations elucidated electronic framework effects on enantioselectivity for (salen)Mn heterogenized in a metal-organic framework (MOF). The correlations also enabled fast ligand scree...