saffron (crocus sativus l.), the most valuable medicinal food product, belongs to the iridaceae family, which has been widely used as a coloring and flavoring agent. the stigmas contain three major compounds; crocins (carotenoid compound responsible for color), picrocrocin (responsible for taste) and safranal (responsible for odor). it has been used for medicinal purposes, as a spice and condim...

background: hexachlorobutadiene (hcbd) is a potent nephrotoxin in rodents, which can cause degeneration, necrosis and regeneration in renal tubular epithelial cells. it has been shown that safranal, the active ingredient of saffron, has a protective effect against ischemic injuries. the aim of this study was to examine the protective effect of safranal against hcbd-induced nephrotoxicity in rat...

Saffron is a spice derived from the flower of Crocus sativus L., which has special aroma, colour and odour influencing positively its economic value. In this context, ten saffron ecotypes were screened for their biochemical composition antioxidant activity. The samples also analysed using GC-MS LC-MS to determine content volatile phenolic compounds, respectively. results revealed statistically ...

All retinal disorders, regardless of their aetiology, involve the activation of oxidative stress and apoptosis pathways. The administration of neuroprotective factors is crucial in all phases of the pathology, even when vision has been completely lost. The retina is one of the most susceptible tissues to reactive oxygen species damage. On the other hand, proper development and functioning of th...

the substances responsible for saffron’s characteristic quality are crocins, picrocrocin, and safranal. the drying process is critical to the saffron quality as measured by levels of secondary metabolites, crocin (color and anti-tumor properties), picrocrocin (taste), and safranal (aroma). four different dehydration methods were evaluated: iranian traditional method (room temperature); dehydrat...

  Objective(s): The effect of the extract of Crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined.   Materials and Methods: Ovalbumin (OA) sensitized guinea pigs were given drinking water alone (group S), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n...

Objective(s) Anti-Helicobacter pylori effects of saffron (Crocus sativus L., Iridacea) and its major constituents, crocin and safranal, were evaluated. Materials and Methods Macerated aqueous and methanol extracts tested against 45 clinical isolates of Helicobacter pylori, using paper disc diffusion method (DDM) on modified egg yolk emulsion agar (EYE agar). Four antibiotics also tested agai...

Safranal, the main component of Crocus sativus essential oil, is thought to be the main cause of saffron unique odor. It is now about eighty years that this compound has been discovered and since then different scientific experiments have been done investigating its biological-pharmacological activities. Safranal effects in CNS have been more attractive to scientists and an escalating number of...