Fault-tree analysis is applied to technological systems to determine the probability of system’s failure modes with unacceptable consequences, called “critical states”. As many Fault-trees as the number of system’s critical states are constructed and analysed; when their probabilities are deemed not acceptable, the Importance and Sensitivity Analysis (ISA) is applied to improve the system safet...

Fault Tree Analysis (FTA) has become a popular tool for use in the Space Industry for the System Safety Engineer. The fault tree is used for everything from tracking hazard reports to investigating accidents, as well as presentations to management. Yet, experience in the space industry has shown the fault tree is used most often for purposes other than its original intent, namely for evaluating...

This white paper lays out some foundational information about different approaches to safety: how various industries differ in their approaches to safety engineering, and a comparison of three general approaches to safety (system safety, industrial safety engineering, and reliability engineering). An attempt is made to lay out the properties of industries and systems that make one approach more...

background: hormone therapy is currently the mainstay in the management of locally advanced and metastatic prostate cancer. we performed a systematic review to compare safety, efficacy and effectiveness of degarelix, a new gonadotropin-releasing hormone (gnrh) antagonist (blocker), versus gonadotropin-releasing hormone (gnrh) agonists. methods: medline, web of science and the cochrane library w...

precise identification of the risks of power plants as a part of a comprehensive safety analysis is recommended by monitoring organizations. assessment and risk management techniques in industrial activities through the use of preventive approach to identify hazards , assess and control safety - health risks unit is studied. in this study, risks and effects of abadan gas power plant were studie...

Safety case development is not a post-development activity, rather it should occur throughout the system development lifecycle. The key components in a safety case are safety arguments. Too often, safety arguments are constructed without proper reasoning. Inappropriate reasoning in safety arguments could undermine a system’s safety claims, which in turn contributes to safety-related failures of...

background: patient safety is a serious global public health issue. estimates show that every day many patients are harmed while receiving hospital care. health care staff plays a key role in providing quality and safe patient care, especially physicians who are main members of the medical team and a critical element in patient safety efforts. objective: the current study used a theory of plann...