The none reducing sugar floridosides and sucrose, which are abundant in photosynthetic red algae and green plants, respectively, are recognized as the initial stable neutral saccharides produced in large quantity. In the fifties, when the author started a research program on the assimilation of translocated neutral saccharides in sink organs, live red algae were not readily available and the st...

We have measured the temperature dependence of the far-infrared vibrational modes of polycrystalline saccharide molecules in the frequency range 0.1–3.0 THz using a time-resolved terahertz spectroscopy system. Coherent measurement of the transmitted terahertz electric fields showed distinct absorption features, in both monosaccharides and disaccharides, originating from interand intra-molecular...

The question of the molecular weight of the specific polysaccharides is one of great importance for an understanding of the mechanism of immune reactions. It has been found that the precipitin reaction, for example, may be accounted for as a chemical combination of antigen (or haptene) with antibody globulin in proportions depending on the relative amounts of antigen (haptene) and antibody pres...

1. Microsomal fractions of lactating rabbit mammary gland incubated with UDP-glucose formed lipid-linked mono- and oligo-saccharides. The lipid-linked monosaccharide had chromatographic properties similar to those of dolichol phosphate mannose and yielded glucose on acid hydrolysis. 2. Incubation of the microsomal fraction with GDP-[U14C]-mannose yielded an oligosaccharide lipid of approximatel...

The synthesis of xylosyloligosaccharides from beta-(1----4)-xylobiose in the presence of D-mannose by transxylosylation with beta-xylosidase from Aspergillus niger IFO 6662 was studied. At first, the transxylosylation products were separated by charcoal column chromatography in 5% ethanol elution into three peaks, P-1, P-2, and P-3. They were further separated on thin layer chromatography, and ...

An improved synthesis of a rhodamine boronic acid indicator is reported. This compound is used in an optimized data collection protocol for wavelength- and time-dependent selectivity of sugars such as fructose and ribose derivatives. One indicator is thus used to selectively distinguish structurally related sugar analytes.

Carborane-appended 5-thio-Dglucopyranose (TDG) and deoxyribose derivatives were synthesized and evaluated for accumulation in cancer cells, cytotoxicity, and efficacy in an in vitro boron neutron capture therapy (BNCT) assay. The nidocarborane-appended sugar conjugates were found to be less cytotoxic than their closo-carborane analogues. Biological evaluation with human hepatocellular carcinoma...