A steric-hindrance model has been used to explain the regulation of muscle contraction by tropomyosin-troponin complex. The regulation of binding was studied by microscopic observation of mixtures of fluorescent subfragment 1 (S1) with rigor myofibrils at different actin-to-S1 ratios and in the presence and absence of calcium. Procedures were adapted to protect the critical thiols of S1 before ...

Let X be a non empty normed structure and let s1 be a sequence of X. The functor ( ∑ κ α=0(s1)(α))κ∈N yielding a sequence of X is defined as follows: (Def. 1) ( ∑ κ α=0(s1)(α))κ∈N(0) = s1(0) and for every natural number n holds ( ∑ κ α=0(s1)(α))κ∈N(n + 1) = ( ∑ κ α=0(s1)(α))κ∈N(n) + s1(n + 1). One can prove the following proposition (1) Let X be an add-associative right zeroed right complementa...

STUDY DESIGN Biomechanical, cadaveric study. OBJECTIVE To compare the fixation strength of a novel S1 pedicle screw insertion technique in a revision setting to a standard S1 pedicle screw and an L5 pedicle screw. SUMMARY OF BACKGROUND DATA Fusions to the sacrum remain a difficult clinical challenge. Very few salvage techniques exist when a nonunion occurs. METHODS The biomechanical integ...

OBJECTIVES   We identify the contrast volumes needed to reach specific landmarks during S1 transforaminal epidural injections (S1-TFEIs). DESIGN   Prospective, nonrandomized, observational human study. Setting.  Academic/private pain management practice. Subjects.  Forty-two patients undergoing S1-TFEIs were investigated. Thirty-seven patients were included in this study. Interventions.  S1-T...

It is known that ternary complexes of myosin subfragment 1 (S1) with ADP and the Pi analogs beryllium fluoride (BeFx) and aluminum fluoride (AlF4-) are stable analogs of the myosin ATPase intermediates M* x ATP and M** x ADP x Pi, respectively. Using kinetic approaches, we compared the rate of formation of the complexes S1 x ADP x BeFx and S1 x ADP x AlF4- in the absence and in the presence of ...

We show that if F :S1 → S1 is a homeomorphism of the unit circle S1 and the rotation number α(F ) of F is irrational, then the Schröder equation Φ ( F(z) = e2πiα(F Φ(z), z ∈ S1, has a unique (up to a multiplicative constant) continuous at a point of the limit set of F solution. We apply this result to prove that if F is a non-trivial continuous and disjoint iteration group or semigroup on S1 an...

S1 Table. Properties of available TCR structures. For each X-ray structure TCR names used in the literature are listed and the relevant TCR chains within one biological unit are indicated. Loci and alleles of the TRAV, TRBV, TRAJ, and TRBJ were assigned using the IMGT Gene/DB [1] and the sequences of the CDR loops are listed for comparison of the different subtypes (Mutations within the framewo...

In this article we present s1, a family of logics that is useful to disprove propositional formulas by means of an anytime approximation process. The systems follows the paradigm of a parameterized family of logics established by Schaerf’s and Cadoli’s system S1. We show that s1 inherits several of the nice properties of S1, while presenting several attractive new properties. The family s1 deal...

The starfish SALMFamide neuropeptides S1 (GFNSALMFamide) and S2 (SGPYSFNSGLTFamide) are the prototypical members of a family of neuropeptides that act as muscle relaxants in echinoderms. Comparison of the bioactivity of S1 and S2 as muscle relaxants has revealed that S2 is ten times more potent than S1. Here we investigated a structural basis for this difference in potency by comparing the bioa...