Background: Glanzmanns Thrombasthenia (GT) is a GPIIb/IIIa platelet surface receptor condition that defined by lack of aggregation, either qualitatively or quantitatively. This receptors physiological function to bind various sticky plasma proteins aid adhesion and ensuring the development thrombus at sites vascular damage. Patient GT typically presents with menorrhagia, easy bruising, epistaxi...

PLASMA CLOTTING FACTOR is deficient in most of the “experiments of nature” that have helped to further our understanding of the mechanism of blood coagulation and hemostasis, but in thrombasthenia the defect lies in the platelets which are unable to promote clot retraction. Thrombasthenic patients usually have a mild to moderately severe hemorrhagic diathesis, with a prolonged bleeding time. Th...

Patients with inherited bleeding disorders are rare in obstetric practice but present with prolonged bleeding even after minor invasive procedures. They require a combined approach with obstetric and hematological management of each case, including the neonatal management of a possibly affected fetus. We present the case of a pregnancy in a patient with combined Factor VII deficiency and Glanzm...