background & objective: streptococcosis is one of the bacterial infections in fish, especially rainbow trout which infects brain and nervous systems of fish and is caused by s. iniae . estimation of the impact of disease prevalence by s. iniae in fish farming in some countries is reported about 100 million dollars per year. some of the most effective proteins in pathogenicity of these bacteria ...

Angelica dahurica (Fisch. Ex Hoffm) is an important traditional Chinese herb which is widely used in curing acne, ulcers, carbuncles, rheumatism, headaches and toothaches. A systematic antifungal bioassayguided fractionation of the ethyl acetate extract from A. dahurica led to the isolation of six coumarins, namely, suberosin, bergapten, alloimperatorin, xanthotoxol, 5-methoxy-8-hydroxypsoralen...

Systemic pathogens have developed numerous strategies for evading the defenses of the host, permitting dissemination and multiplication in various tissues. One means of survival in the host, particularly in the bloodstream, has been attributed to the ability to avoid phagocytosis via capsular polysaccharide. To further define the virulence capacity of Streptococcus iniae, a zoonotic pathogen wi...

Bass hepcidin was purified from the gill of hybrid striped bass (Morone chrysops x Morone saxatilis) based on antimicrobial activity against Escherichia coli. This 21-amino acid peptide has 8 cysteines engaged in 4 disulfide bonds and is very similar to human hepcidin, an antimicrobial peptide with iron regulatory properties. To gain insight into potential role(s) of bass hepcidin in innate imm...

We have used a PCR assay based on the use of degenerate primers in order to characterize an internal fragment (sodA(int)) representing approximately 85% of the genes encoding the manganese-dependent superoxide dismutase in various streptococcal type strains (S. acidominimus, S. agalactiae, S. alactolyticus, S. anginosus, S. bovis, S. constellatus, S. canis, S. cricetus, S. downei, S. dysgalacti...

Bass hepcidin was purified from the gill of hybrid striped bass (Morone chrysops Morone saxatilis) based on antimicrobial activity against Escherichia coli. This 21-amino acid peptide has 8 cysteines engaged in 4 disulfide bonds and is very similar to human hepcidin, an antimicrobial peptide with iron regulatory properties. To gain insight into potential role(s) of bass hepcidin in innate immun...

Toll-like receptor (TLR) 3 is an important member of the TLR family, recognizes invading pathogens specifically double-stranded RNA viruses. In this paper, turbot (Scophthalmus maximus) TLR3 gene (smTLR3) was cloned and its expression profiles were analyzed with RT-PCR and In situ hybridization. Then its expression was investigated in cultured peripheral blood leukocytes (PBLs) simulated with p...

drum Sciaenops ocellatus mortalities associated with Streptococcus iniae infection. et al. Invasive infections due to a fish pathogen, Streptococcus iniae. S. Streptococcus iniae, a human and animal pathogen: specific identification by the chaperonin 60 gene identification method. To the Editor: A recent extensive study on global distribution of rubella virus genotypes by Zheng et al. (1) showe...

The Streptococcus iniae UEL-Si1 strain was isolated from diseased Nile tilapia within the Paranapanema River Basin, Northern Paraná, Brazil. This is an emerging infectious disease agent of fish from Brazil, and sequencing of the complete genome is fundamental to understanding aspects relative to pathogenesis, infection, epidemiology, and immunity.