Immunogold studies of normal human kidney and common human kidney cancers were performed using polyclonal antibodies to antioxidant enzymes, including antibodies to copper, zinc and manganese superoxide dismutases, catalase, glutathione peroxidase, and glutathione S-transferases and their subunits. Normal tissue adjacent to human renal tumors had the same antioxidant enzyme immunoreactive prote...

Background: Toddalia asiatica (Linn) Lam is a woody vine that is used medicinally in China, India, and East Africa. The aim of the present study was to examine the antioxidant and antibacterial activity of the roots of Toddalia asiatica (Linn) Lam (TA). Materials and Methods: The antioxidant capacity of TA roots was determined using 1,1 iphenyl-2-picrylhydrazyl (DPPH), 2,2 ́-azino-bis(3-ethylben...

Recently, interest in plant-derived food additives has grown mainly because synthetic antioxidants suffer from several drawbacks. Some plants are traditionally used for both food and medicine in Iran. Aqueous and methanolic extracts of Smyrnium cordifolium Boiss leaves and stems and Sinapis arvensis L leaves, stems and flowers were prepared and evaluated for their total phenolic content (TPC), ...

The goal of this study was to test the hypothesis that increases in oxidative stress in Dahl S rats on a high-salt diet help to stimulate renal nuclear factor-kappaB (NF-kappaB), renal proinflammatory cytokines, and chemokines, thus contributing to hypertension, renal damage, and dysfunction. We specifically studied whether antioxidant treatment of Dahl S rats on high Na intake would decrease r...

This study was designed to examine the in vitro antioxidant activities and total phenolic contents of the methanolic extracts from male inflorescence of Salix aegyptiaca L. grown in Iran. The methanolic extract (ME) and its three fractions including water (WF), butanol (BF) and chloroform (CF) were prepared and then their antioxidant activities, as well as total phenolic contents, were evaluate...

This study was designed to examine the in vitro antioxidant activities and total phenolic contents of the methanolic extracts from male inflorescence of Salix aegyptiaca L. grown in Iran. The methanolic extract (ME) and its three fractions including water (WF), butanol (BF) and chloroform (CF) were prepared and then their antioxidant activities, as well as total phenolic contents, were evaluate...

Background Any factor like diabetes that changes the oxidant/antioxidant balance in favor of oxidants could possibly disrupt the physiologic function of ovaries. So, we have investigated the effect of vitamin E and Se supplements on antioxidant defense in ovaries of diabetic rats with focus on Xanthine dehydrogenase/oxidase (XDH/XO) and Aldehyde oxidase (AO) activities. MaterialsAndMethods This...

Antioxidants protect against damage from free radicals and are believed to slow the ageing process. Previously, we have reported the high antioxidant activity of 70% methanolic Sonchus oleraceus L. (Asteraceae) leaf extracts. We hypothesize that S. oleraceus extracts protect cells against H2O2-induced senescence by mediating oxidative stress. Premature senescence of young WI-38 cells was induce...

background and objectives:scrophularia variegata m. beib. (scrophulariaceae) is a medicinal plant, used for various inflammatory diseases in iranian traditional medicine. in the present study, we evaluated the immune modulation and antioxidant effects of the hydroalcoholic extract of s.  variegata. methods: the splenocytes were harvested from the spleen of balb/c mice and were cultured. the spl...