PURPOSE To evaluate factors associated with rapid rate of progression (ROP) of right ventricular (RV) dilation by cardiac MRI in repaired tetralogy of Fallot (TOF) patients. MATERIALS AND METHODS All patients with repaired TOF with two MRIs were included. RV volumes and function were assessed by MRIs performed on a GE 1.5 Tesla (T) platform. The ROP of RV dilation was calculated as the differ...

Resveratrol (RV) is a natural polyphenol compound with a wide range of activities, including inhibition of human bladder cancer (HBC) cell growth. Because RV is rapidly metabolized and has poor bioavailability, it is unclear whether the antitumor activity is due to RV or its metabolites. We therefore used liquid chromatography-mass spectroscopy, qRT-PCR, immunocytochemistry and western blotting...

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling leading to right ventricular (RV) hypertrophy and failure. Intralipid (ILP), a source of parenteral nutrition for patients, contains γ-linolenic acid and soy-derived phytoestrogens that are protective for lungs and heart. We, therefore, investigated the therapeutic potential of ILP in preventing and rescuing...

Acute right ventricular (RV) hypertension and failure occur clinically. In this study we examined the mechanism of RV failure. Adult dogs were studied acutely under anesthesia; dogs were instrumented for measurement of pressures and right coronary artery blood flow. Myocardial blood flow and cardiac output were determined with radionuclide-labeled microspheres, and the presence of ischemia was ...

Accurate quantitation of right ventricular (RV) volumes and systolic function provides important diagnostic and prognostic information in a wide range of conditions. In the case of heart failure, a preserved RV ejection fraction (RVEF) is associated with improved long-term survival. The most recent task force criteria for the diagnosis of arrhythmogenic RV cardiomyopathy require the presence of...

Accurate quantitation of right ventricular (RV) volumes and systolic function provides important diagnostic and prognostic information in a wide range of conditions. In the case of heart failure, a preserved RV ejection fraction (RVEF) is associated with improved long-term survival. The most recent task force criteria for the diagnosis of arrhythmogenic RV cardiomyopathy require the presence of...