Clinical distinction between pityriasis amiantacea-like tinea capitis and pityriasis amiantacea due to noninfectious inflammatory diseases is a troublesome task, with a significant likelihood of diagnostic errors/delays and prescription of inappropriate therapies. We report a case of pityriasis amiantacea-like tinea capitis with its dermoscopic findings in order to highlight the usefulness of d...

Pityriasis amiantacea is a rare cutaneous reaction pattern to various underlying inflammatory diseases of the scalp. The clinical findings are very characteristic but often under-recognized. This condition can lead to scarring alopecia, and can be refractory to conservative treatment. It is therefore important to recognize the condition so that appropriate treatment can be initiated promptly.

Pityriasis rubra pilaris is a rare chronic inflammatory papulo-squamous skin disease, the pathogenesis of which still unclear. The pathological essence disease associated with violation keratinization against background hyperactivity keratinocytes subsequent inflammation, as well vitamin A dysmetabolism and weakening protein-binding fiction liver. Unfortunately, treatment complex inconsistent i...

PRP may be underdiagnosed because it has many mimics, the most important of which is psoriasis. The cause is unknown, but genetic and autoimmune components are likely. Although PRP is self-limited in many cases, the disease is highly variable and impairs quality of life. R.S. approached me about treatment. Should he try acitretin (Soriatane), a systemic retinoid that may hasten clearance? R.S. ...

Imiquimod is an immunomodulator with both antitumor and antiviral properties. It is currently available in two cream formulations as Aldara (imiquimod 5%) and the newly approved Zyclara (imiquimod 3.75%). Imiquimod has been associated with localized erythema, crusting, and scaling at the site of application. However, more severe generalized skin eruptions including erythema multiforme, psoriasi...

Psoriasis is a chronic, relapsing dermatose characterized by erythematous scaly plaques. Histopathological signs parakeratosis, losing of granular layer, acanthosis, papillomatosis, microabscess, capillary proliferation, excessive mitosis up to 50 fold. Differential diagnosis of psoriasis should be done with all bacterial-viral diseases, tumors, precancerous lesions, mycosis fungoides, subacute...

The differential diagnosis of erythemato-squamous diseases is a difficult problem in dermatology. Artificial Neural Network (ANN) classifies the given samples when trained and nearly 98 % classification accuracy is achieved. Generalized Feed Forward Neural Network (FFNN) can solve the multivariable classification problem of determination of skin disease. ANN approach is studied to determine the...

Introduction The CARD14 (Caspase Recruitment Family Member 14) locus encodes a scaffold protein that mediates NF-kB signalling in keratinocytes and is therefore crucial to the maintenance of skin immune homeostasis. In keeping with this notion, gain-of-function CARD14 mutations have been observed in patients with plaque psoriasis and pityriasis rubra pilaris, two skin disorders mediated by abno...