background: clopidogrel is one of the most commonly prescribed drugs to prevent ischemic events following coronary syndromes or stent placement. however, impaired responses to therapy as well as resistance are also reported. genetic variants play an important role in clopidogrel biotransformation to its active metabolite that may subsequently influence the clopidogrel antiplatelet effect. the o...

conclusions the prevalence of undiagnosed ihd in the hd patients was considerable. we, therefore, suggest that ihd be assessed in hd patients, especially those at high risk due to positive family history of cad, hypertension, left ventricular hypertrophy, diabetes mellitus, kt/v < 1.2, low ferritin levels, and high levels of intact parathyroid hormone. results sixty-nine hd patients were studie...

proximity of the vagus nerve to a patent ductus arteriosus (pda) can cause traction or entrapment of vagus nerve during surgical closure of the in rare occasions. this can lead to a life threatening postoperative bradycardia. herein, we report a case of bradycardia caused by unexpected irritation of the vagal trunk by the end of operation. the patient was managed by re-opening the chest, lung r...

now-a-days truncus arteriosus has been known as “common arterial trunk” (cat) and is an uncommon congenital cardiac defect presenting in about 1-3% congenital heart disease. environmental and genetic factors effects on incidence of cat and other conotruncal anomalies. the majority patients with cat and 22q11 deletion have other anomalies such as hypoplasia or aplasia of the thymus or parath...

introduction takotsubo cardiomyopathy (tcmp) is a rare acute cardiomyopathy characterized by acute chest pain syndrome, similar to myocardial infarction, except that no significant stenosis is observed on coronary angiography in patients with this condition; these findings aid the diagnosis of tcmp. case presentation we discuss an unusual case of tcmp in a 45-year-old woman with complete heart ...

background and aims: coronary heart diseases (chds) contribute to mortality, morbidity, disability, productivity and quality of life. this study was aimed to determine the prevalence of major risk factors for chd in the provinces of iran. methods:this study reported pre-existing data and was of secondary, descriptive type. prevalence of non-communicable disease (ncd) risk factors was defined fo...

background: cardiovascular disease (cvd) is one of the leading causes of death in the world. one of its most insidious forms is coronary heart disease (chd) which decreases patient's quality of life. research indicates that psychological factors are interrelated with coronary heart disease patients' quality of life. in the present study, the role of type d personality and emotional intelligence...

Pneumococcal disease (including community-acquired pneumonia and invasive pneumococcal disease) poses a burden to the community all year round, especially in those with chronic underlying conditions. Individuals with COPD, asthma or who smoke, and those with chronic heart disease or diabetes mellitus have been shown to be at increased risk of pneumococcal disease compared with those without the...

Desmoplastic small round cell tumor is a rare malignant tumor that occurs primarily in young males. Here, a case of small round cell tumor in an adult male successfully treated with a curative concurrent chemoradiotherapy is presented. A 58-year-old man had an intrapelvic tumor. Surgical resection was attempted, but the tumor was unresectable. Needle biopsy was performed and the diagno...