This paper describes the process of composing problems that are suitable for competitions in linguistics. The type of problems described is “Rosetta Stone”—a bilingual problem where typically one of the languages is unknown, and the other is the native language of the person solving the problem. The process includes selecting phenomena, composing and arranging the data and assignments in order ...

Abstract A recent work aided by Rosetta in situ measurements set constraints on the dust-to-gas mass emission ratio and size distribution of dust escaping nucleus comet 67P/Churyumov–Gerasimenko near perihelion. Here we use this information along with other observables/parameters as input into an analytical model aimed at estimating number density electrons attached to particles position Rosett...

The Rosetta project has its roots in an earlier research project at Philips Research Laboratories, called PHLIQA (cf. Bronnenberg et al. (1)). In this project a system was developed that answered questions posed in natural English about information stored in a data base. The first component of that system had the task to convert a question into an expression of a logical language. This was done...

The Western Pacific amyotrophic lateral sclerosis and parkinsonism-dementia complex (ALS-PDC) has been described as a Rosetta Stone that bears the essential clue to understanding the etiopathogenesis of related neurodegenerative diseases. The three clinical forms (ALS, atypical parkinsonism with dementia, and dementia alone) have a single pathology (polyproteinopathy, notably tauopathy), just a...

An approach to the de novo structure prediction of proteins is described that relies on surface accessibility data from NMR paramagnetic relaxation enhancements by a soluble paramagnetic compound (sPRE). This method exploits the distance-to-surface information encoded in the sPRE data in the chemical shift-based CS-Rosetta de novo structure prediction framework to generate reliable structural m...

Amyloid fibrils are the pathological hallmark of a large variety of neurodegenerative disorders. The structural characterization of amyloid fibrils, however, is challenging due to their non-crystalline, heterogeneous, and often dynamic nature. Thus, the structure of amyloid fibrils of many proteins is still unknown. We here show that the structure calculation program CS-Rosetta can be used to o...

This paper describes a design case-study undertaken as part of the language design validation for the Rosetta System Level Description Language. The system under consideration is a dualspring mechanical system. A physical model is constructed, describing the static characteristics of springs and the requirements and constraints applying to the system. It is demonstrated that the declarative mod...

The aim of the study was to optimize conditions for producing Salmonella Enteritidis recombinant heat shock protein 60 (rHsp60). Seven Escherichia coli host strains (Rosetta, Turner, C41, C43, Origami, BL21pLys, Rosetta pLys) were transformed by a recombinant plasmid containing Hsp60 gene from Salmonella Enteritidis, and then cultured and induced by isopropyl-beta-D-thiogalactopyranoside (IPTG)...

Introduction: The Rosetta mission to comet 67/P Churyumov-Gerasimenko is also scheduled to do two asteroid fly bys. The first of these was on Sept. 5 th , 2008, when the spacecraft flew within 800 km of asteroid 2867 Steins. The timing of the encounter meant that the surface of the asteroid (as seen from the spacecraft) was well illuminated, providing good imaging conditions. As well as providi...