نتایج جستجو برای: ro performances
تعداد نتایج: 64498 فیلتر نتایج به سال:
Biomedical Research Models, Inc. In vivo receptor occupancy (RO) is a valuable tool used in preclinical drug development to confirm target engagement and faci litate selection of compounds for further development. We have been using radioligand-based RO as means of measuring target engagement in the rat brain. In this approach, compounds of interest are peripherally injected prior to intravenou...
BACKGROUND In patients with autoimmune disease, anti-Ro/SSA antibodies (anti-Ro/SSA) are responsible for a novel autoimmune-associated long-QT syndrome by targeting the hERG potassium channel and inhibiting the related current (IKr). Because anti-Ro/SSA are also present in a significant proportion of healthy subjects and may be associated with torsades de pointes (TdP) arrhythmia, we tested the...
In this article, the performance of silicon FinFET is compared with carbon nanotube (CNT-FET) and 2-D field-effect transistors (2D-FETs) for upcoming node CMOS logic application. Based on experimental results, a 17-stage ring oscillator (RO) circuit implemented using compact models to analyze stage-delay energy-delay performances. A tightly positioned 20- 10-nm channel-length-based CNT-FET enha...
Kapal Ro-Ro penyeberangan di Indonesia menjadikan ukuran GT sebagai patokan untuk menentukan kapasitas kendaraan yang dapat diangkut oleh kapal. Namun, digunakan belum bisa merepresentasikan angkut sebuah kapal penyeberangan, karena nilai jual penyebrangan berupa luasan main deck/car deck dan berat muatan. Ukuran lane meter penyeberangan. Lane merupakan suatu metode mengukur ruangan Ro-Ro, mana...
Antibodies against a conserved RNA-binding protein, the Ro 60-kDa autoantigen, occur in 24-60% of all patients with systemic lupus erythematosus. Anti-Ro antibodies are correlated with photosensitivity and cutaneous lesions in these patients and with neonatal lupus, a syndrome in which mothers with anti-Ro antibodies give birth to children with complete congenital heart block and photosensitive...
In this paper we study polynomial identity testing of sums of k read-once algebraic branching programs (Σk-RO-ABPs), generalizing the work of Shpilka and Volkovich [1, 2], who considered sums of k read-once formulas (Σk-RO-formulas). We show that Σk-RO-ABPs are strictly more powerful than Σk-RO-formulas, for any k ≤ ⌊n/2⌋, where n is the number of variables. Nevertheless, as a starting observat...
We have recently isolated a cDNA encoding a novel human receptor-type tyrosine phosphatase, termed PTP-RO (for a protein tyrosine phosphatase receptor omicron), from 5-fluorouracil-treated murine bone marrow cells. PTP-RO is a human homologue of murine PTPlambda and is related to the homotypically adhering kappa and mu receptor-type tyrosine phosphatases. PTP-RO is expressed in human megakaryoc...
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