this commentary is the first of what I hope will be a regular column that will highlight important discoveries in the basic neurosciences. specifically, my intent is to inform those in the clinical neurosciences who usually do not have the time to read and/or access high impact neuroscience journals about breakthroughs that have the potential to be transformative in our understanding and treatm...

Securing the multicast communication model is a strategic requirement for effective deployment of large scale business multi-party applications (TV over Internet, Video-on-Demand (VoD), video-conferencing, interactive group games, .). One of the main issues in securing multicast communication is the authentication service; a keystone of every secure architecture. Even though several authenticat...

The morphology of hyperplastic pituitaries in seven human growth hormone-releasing factor (hGRF) transgenic mice were compared to those of two normal control mice. Under continuous stimulation by hGRF, both the total volume of the pituitary and the size of individual cells increased, and a nodular lesion, designated a "hypertrophic nodule", was identified. Immunohistochemically, the hyperplasti...

Viral recognition is mediated by different classes of PRRs (pattern-recognition receptors) among which the TLRs (Toll-like receptors) and the RLHs [RIG (retinoic-acid-inducible)-like helicases] play major roles. The detection of PAMPs (pathogen-associated molecular patterns) by these PRRs leads to the initiation of signalling pathways that ultimately result in the activation of transcription fa...

Same as Report (SAR) 18. NUMBER

Background: Based on classical two cell- two-gonadotropin theory, in the follicle, FSH and LH put on their main effects on the granulosa and theca cells. LH is essential for androgens production. Androgens as precursor, is used for estradiol production by granulosa cells under aromatase activity. Profound suppression of LH concentrations in some normogonadotropic patients can cause several adve...