Onchocerciasis (river blindness) is caused by the parasitic worm Onchocerca volvulus, transmitted to humans by the bite of infected black flies of the genus Simulium, and is characterized by chronic skin disease, severe itching, and eye lesions that can progress to complete blindness. Currently, among approximately 123 million persons at risk for infection in 38 endemic countries, at least 25.7...

Background: Color vision has an important role in daily activities and also learning special talents in different jobs, especially in the field of medicine. However, they are many people all over the world that has no insight into their color blindness and choose the study fields that are completely dependent on vision. Due to the importance of color vision in the field of medicine, we conducte...

Background Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca volvulus. A single ivermectin (standard) dose clears the skin-dwelling microfilarial progeny of adult worms (macrofilariae) and temporarily impedes the...

BACKGROUND Onchocerca volvulus and lymphatic filariae, causing river blindness and elephantiasis, depend on endosymbiotic Wolbachia bacteria for growth, development, fertility, and survival. Clinical trials have shown that doxycycline treatment eliminates Wolbachia, causing long-term sterilization of adult female filariae and effecting potent macrofilaricidal activity. The continual reinfection...

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There is an error in the antepenultimate sentence of the abstract. The number of treatments is incorrect. The correct sentence is: The control scenario requires community-directed treatment with ivermectin beyond 2045 with around 2.63 billion treatments over 2013–2045; the elimination scenario, until 2028 in areas where feasible, but beyond 2045 in countries with operational challenges, around ...

BACKGROUND Onchocerciasis (river blindness) is endemic mostly in remote and rural areas in sub-Saharan Africa. The treatment goal for onchocerciasis has shifted from control to elimination in Africa. For investment decisions, national and global policymakers need evidence on benefits, costs and risks of elimination initiatives. METHODS We estimated the health benefits using a dynamical transm...

purpose: to determine the prevalence and causes of blindness and low vision in yazd provice in 2008. methods: a population-based cross-sectional study was performed on inhabitants of in yazd province in 2008. using multistage cluster sampling, sample size was calculated based on the distribution of the total population of yazd province derived from national census and estimated rates of blindne...

color -blindness is the inability to perceive differences between some color that other people can distinguish. using a literature search , the results indicate the prevalence of color vision deficiency in the medical profession and its on medical skills. medical laboratory technicians and technologists employees should also screen for color blindness. this research aimed to study color blindne...