To evaluate the accuracy of ultrasound in early detection of chorionicity and amnionicity in twin pregnancies and evaluate the role of operator-experience, a prospective follow up of 87 consecutive twin pregnancies was performed. Chorionicity and amnionicity were determined by 17 different observers, divided in 2 groups on the basis of their experience, using a composite of US markers at the fi...

BACKGROUND Data on the safety of selective serotonin-reuptake inhibitors (SSRIs) in pregnancy are inconsistent. We examined associations between SSRI use during early pregnancy and risk of congenital malformations in infants. METHODS Set in Northern Denmark, our population-based prevalence study included 216,042 women who had a live birth after the 20th week of gestation. We compared the prev...

The objective of this study was to determine the concentration of serum l-arginine in healthy pregnant women and infant cord blood and to compare them with those in patients with pregnancy-induced hypertension (PIH). The serum concentration of l-arginine in normal pregnant women at early gestation (n = 186) was determined and analyzed based on maternal factors such as the age, pre-pregnancy bod...

Background: Early diagnosis of gestational diabetes is one of the most important applications of taking care of during pregnancy. The current study was done to find the correlation between hemotocrit in the first trimester of pregnancy with gestational diabetes in women who referred to Milad Hospital in Tehran in 2009-2010. Materials and Methods: A prospective cohort study was conducted on 700 ...

BACKGROUND Increased total homocysteine (tHcy) may be associated with placental-mediated adverse pregnancy outcomes, but few prospective studies have measured tHcy before pregnancy outcome. This study was undertaken to determine whether increased tHcy measured in early pregnancy is associated with pregnancy loss, gestational hypertension (GH), preeclampsia, or small for gestational age (SGA) in...

the original biophysical profile is time consuming and costly. this study was performed to compare diagnostic value of the original fetal biophysical profile to the modified biophysical profile. patients were selected from high risk pregnancies referred for fetal assessment and were randomly assigned to two groups. the measures of outcomes were perinatal mortality, cesarean section for abnormal...

BACKGROUND Anaemia in pregnancy is a major public health and economic problem worldwide, that contributes to both maternal and fetal morbidity and mortality. OBJECTIVE The aim of the study was to calculate the prevalence of anaemia in early pregnancy in a cohort of 'low risk' women participating in a large international multicentre prospective study (n = 5 609), to identify the modifiable ris...

Women with gestational diabetes mellitus (GDM) have higher rates of foetal macrosomia, shoulder dystocia and pregnancy-induced hypertension, and are at higher risk of developing type 2 diabetes. Herein, we introduce a new conceptual term, "gestational prediabetes", which requires the absence of diabetes before pregnancy, and the presence of blood glucose levels (or a related marker) in early pr...

a comparative study of pregnancy results in adolescents and young mothers referred to the motazedi hospital in kermanshah n rezavand , md m zangane , md sh malek khosravi , md m rezaee , phd received: 25 april, 2009 accepted: 27 july, 2009 abstract: background & aims: pregnancy in early years of reproductive period has been considered as high-risk pregnancy. considering high prevalence of such ...

In 2010, the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) panel published consensus-based recommendations on the diagnosis and classification of hyperglycemia in pregnancy (1). Within that document, the recommendations regarding early pregnancy testing were designed to facilitate early detection and treatment of hyperglycemia (HbA1c $6.5% [48 mmol/mol], fasting ...