introduction autologous plasma-rich platelet (prp) is a human platelet concentrated product which is in low volume of plasma. using prp in rejuvenation and resolution of some cosmetic problems has been already popular in many countries and also in iran. as no study performed in this field in iran and regarding the high prevalence of using prp in society with no validate references in the case o...

objective: to determine the effects of platelet rich plasma prp on healing rates of long bone non-:union: fracture. method: this was a randomized double-blind placebo controlled clinical trial being performed in a 12-month period. we included 75 adult (>18 years) patients suffering from long bone (femur, tibia, humerus and ulna) non-:union: fracture who were randomly assigned to receive 5ml prp...

background: the cultured mesenchymal stem cells (msc) have been used in many clinical trials however, there are still some concerns about the cultural conditions. one concern is related to the use of fbs as a widely used xenogeneic supplement in the culture system. human platelet-rich plasma (hprp) is a candidate replacement for fbs. in this study, the effect of hprp on msc proliferation and os...

Objective to compare the inflammatory response between platelet rich plasma 20% and autologous serum on cornea after sodium hydroxide exposure. Methods a true experimental study with two groups post-test design. A total of 18 rabbits were used in this allocated into groups. After collecting intravenous blood samples from both group, 20%, respectively, obtained by centrifugation dilution. Alkali...

Background Recently, the clinical use of low power lasers has increased, and it is said that wound healing is accelerated by their irradiation. The aim of this study was evaluation of the effect of platelet-rich plasma on proliferation and differentiation of human dental pulp stem cells with or without Ga-Al-As laser. Methods: In this experimental study, human lower third molar dental pulp c...

Platelet adhesiveness was tested ex vivo in a group of six normal individuals receiving varying doses of a-tocopherol. Adhesion to glass slides coated with fibronectin. collagen. fibrinogen. or plasma proteins was studied by perfusing platelet-rich plasma through a flow chamber that allowed timeand space-resolved observations of platelet adhesion. Platelet adherence was measured in an area of p...

Background: Tendon grafting is mostly required to repair an injury to flexor tendon and due to the importance of this tendon; it needs methods to speed up the re-vitality of the tendon allograft. OBJECTIVES: The aim was to investigate the efficacy of the mesenchymal cells and platelet rich plasma on the hydroxyproline content of frozen allograft tendons after grafting in lamb. METHODS: In this ...

treatment of severe immune thrombocytopenic purpura (itp) accompanied by life-threatening bleeding events is challenging and a combination of treatment measures should be undertaken to rapidly increase the platelet count. herein, we report a case of severe itp in a seven-year-old boy who suffered from massive bleeding which was totally unresponsive to conventional therapeutic interventions. sin...

  Objective: At present, growth factor-containing products such as enamel matrix derivatives, recombinant bone morphogenetic protein (rh-BMP), recombinant platelet derived growth factor and platelet rich plasma (PRP) have gained increasing attention. PRP is an autologous source of platelet growth factors used to enhance healing of soft and hard tissues. PRP has gained popularity due to its auto...