Radiative flux perturbation (RFP) is defined as the top-of-2 the-atmosphere (TOA) radiative imbalance after the atmosphere-land sys-3 tem adjusts fully to an external perturbation, and serves as a useful metric 4 for quantifying climate forcing. This paper presents an effort to address the 5 issue whether a forcing imposed persistently over a specific region may al-6 ter the radiative balance e...

MHC genes in the chicken are arranged into two genetically independent clusters located on the same chromosome. These are the classical B system and restriction fragment pattern-Y (Rfp-Y), a second cluster of MHC genes identified recently through DNA hybridization. Because small numbers of MHC class I and class II genes are present in both B and Rfp-Y, the two clusters might be the result of du...

Postinfarct cardiac hypertrophy is an independent risk factor for heart failure and sudden death. Regression of cardiac hypertrophy has emerged as a promising strategy in the treatment of myocardial infarction (MI). Here we hypothesized that frizzled1 (FZD1), a receptor of the canonical Wnt signaling pathway, is a novel mediator of ischemia-associated cardiac hypertrophy. MI was induced in mice...

BACKGROUND Transgenic RNAi holds promise as a simple, low-cost, and fast method for reverse genetics in mammals. It may be particularly useful for producing animal models for hypomorphic gene function. Inducible RNAi that permits spatially and temporally controllable gene silencing in vivo will enhance the power of transgenic RNAi approach. Furthermore, because microRNA (miRNA) targeting specif...

OBJECTIVES The purpose of this research was to study the effect of dobutamine on left ventricular (LV) filling in ischemic cardiomyopathy (ICM) and to determine whether restrictive filling pattern (RFP) at peak stress has prognostic value. BACKGROUND The prognostic value of RFP at peak stress in ICM is unknown. METHODS A total of 69 patients with ICM were studied by Doppler echocardiography...

MHC genes in the chicken are arranged into two genetically independent clusters located on the same chromosome. These are the classical B: system and restriction fragment pattern-Y (Rfp-Y), a second cluster of MHC genes identified recently through DNA hybridization. Because small numbers of MHC class I and class II genes are present in both B: and Rfp-Y, the two clusters might be the result of ...

Purpose The purpose of this study is to describe the development 14-item reflective fostering fidelity rating (RFFR), an observational system evaluate model group facilitators in Reflective Fostering Programme (RFP), a mentalisation-based psychoeducation programme support foster carers. authors assess usability, dimensionality, inter-rater reliability and discriminative ability RFFR. Design/met...

Using a magnetohydrodynamics numerical code that includes the description of density and pressure evolution and anisotropic thermal conductivity, it is shown that single-helicity states in the reversed-field pinch (RFP) configuration are obtained when the resistivity has a radial profile sharply increasing close to the wall. In contrast, a uniform resistivity produces multiple-helicity states. ...