Reversibility constraints are one aspect of genome-scale metabolic models that has received significant attention recently. This study explores the impact of complete removal of reversibility constraints on the gene essentiality and growth phenotype predictions generated using three published genome-scale metabolic models: the iJR904, the iAF1260, and the iBsu1103. In all three models, the accu...

Reversibility is a concept widely studied in several research fields. Several contributions have been provided in physics and computer science. Reversible computation is characterized by means of invertible properties [1]. Reversibility is studied in computer science also in order to design less dissipative computers. The evolution of quantum systems is described by the time evolution operator ...

Studies on universal Turing machines (UTM) have a long history, and various small UTMs have been given till now [2, 3, 10–12]. Here, we investigate the problem of constructing small UTMs under the constraint of reversibility, which is a property closely related to physical reversibility. Let URTM(m,n) denote an m-state n-symbol universal reversible Turing machine. So far, six kinds of small URT...

Petri nets are a general formal model of concurrent systems which supports both action-based and state-based modelling and reasoning. One of important behavioural properties investigated in the context of Petri nets has been reversibility, understood as the possibility of returning to the initial marking from any reachable net marking. Thus reversibility in Petri nets is a global property. Reve...

Clinically used GPIIb/IIIa blockers are ligand mimetics, and thereby their binding can induce conformational changes of the platelet integrin GPIIb/IIIa. Since the reversibility of these conformational changes may be an important determinant of potential adverse effects of GPIIb/IIIa blockers, we produced a new monoclonal antibody (anti-LIBS-mAb), and by using its binding properties, we investi...

We study the transient response of a colloidal bead which is released from different heights and allowed to relax in the potential well of an optical trap. Depending on the initial potential energy, the system’s time evolution shows dramatically different behaviors. Starting from the short-time reversible to long-time irreversible transition, a stationary reversible state with zero net dissipat...

Symmetric pre-extension is a standard approach to boundary handling for finite-length input vectors with linear phase filter banks. It works with both conventional linear implementations and so-called reversible, or integer-to-integer, implementations of odd-length linear phase (whole-sample symmetric) filter banks. In comparison, significant difficulties arise when using symmetric pre-extensio...

A reversible cellular automaton is one whose evolution, and therefore the entire past history of any con guration, can be uniquely deciphered. There are degrees of reversibility, depending upon whether the con gurations considered are arbitrary, periodic, or quiescent at in nity; which are subsidiary to more general questions of injectivity and surjectivity, within a general perspective of the ...

Recently, deep residual networks have been successfully applied in many computer vision and natural language processing tasks, pushing the state-of-the-art performance with deeper and wider architectures. In this work, we interpret deep residual networks as ordinary differential equations (ODEs), which have long been studied in mathematics and physics with rich theoretical and empirical success...