نتایج جستجو برای: respectively following dna extaction
تعداد نتایج: 1732311 فیلتر نتایج به سال:
Cancer Therapy: Preclinical ImportanceofEGFR/ERCC1 InteractionFollowingRadiation- Induced DNA Damage
Purpose: The epidermal growth factor receptor (EGFR) plays an important role in cellular response to chemotherapy and radiotherapy through modulation of DNA repair. EGFR activates DNA-dependent protein kinase (DNA-PK) stimulating repair ofDNA strand breaks (SB) and interstrand crosslinks (ICL).We investigated the role of EGFR in repair of ionizing radiation (IR)-induced SB independently of DNA-...
Members of the phosphatidylinositol (PI) 3-kinase gene family, including the ataxia telangiectasia gene and the DNA-dependent protein kinase (DNA-PK), are involved in regulating cellular radiosensitivity. We have investigated two structurally unrelated PI 3-kinase inhibitors, wortmannin and LY294002, to determine whether they inhibit DNA-PK and increase cellular radiosensitivity. The PI 3-kinas...
The PrepFiler Forensic DNA Extraction Kit enables isolation of genomic DNA from a variety of biological samples. The kit facilitates reversible binding of DNA with magnetic particles resulting in high DNA recovery from samples with very low and high quantities of biological materials: 0.1 and 40 microL of human blood (donor 2) provided 14 and 2883 ng of DNA, respectively. Following the revised ...
Chromatin assembly factor 1 (CAF-1) is involved in nucleo some assembly following DNA replication and nucleotide excision repair. In Arabidopsis thaliana, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. In this study, we asked whether genomic stability is altered in fas1 and fas2 mutants that are lacking CAF-1 activity. Depletion of either subunit increa...
Clubroot disease resistance has been introgressed from Brassica rapa into canola following different approaches including a B. napus × interspecific cross; however, the details of this cross are not available. To extend our knowledge for introgression to multiple pathotypes, we crossed clubroot-resistant turnip with susceptible and backcrossed F1′s canola. The backcross population was subjected...
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