Blood samples from 104 patients with clinically suspected thrombophilia were analyzed for coagulation factor V Leiden mutation (1691, G-->A) by allele-specific polymerase chain reaction. In 86 individuals (82.7%), the mutation was not detectable, whereas 15 patients (14.4%) were heterozygous and three patients (2.9%) were homozygous for factor V Leiden mutation. Plasma samples from these indivi...

Background: Recent studies suggest that psoriasis may be a pathogenic factor for the metabolic syndrome and atherosclerosis. The aim of our study was to investigate the metabolic state in psoriatic patients in order to clarify the association between psoriasis and insulin resistance.Methods: This single-centre, case- control study was performed between 2008 and 2010 to evaluate the metabo...

Transformation of E. coli cells treated with CaCl(2) to multiple antibiotic resistance by purified R-factor DNA is reported. Drug resistance is expressed in a small fraction of the recipient bacterial population almost immediately after uptake of DNA, but full genetic expression of resistance requires subsequent incubation in drugfree medium before antibiotic challenge. Transformed bacteria acq...

The aim of this work is to optimize the oxidation resistance of ZrB2-SiC-based composites with different additives. Effect of nine factors including SiC, Cf, MoSi2, HfB2 and ZrC contents, milling time of Cf (M.t) and SPS parameters such as temperature, time and pressure on oxidation resistance in four levels was investigated. Taguchi design was applied to explore effective parameters for ...

Vascular endothelial cells importantly contribute to the regulation of vascular smooth muscle tone through the production of a variety of vasoactive substances and by direct electric communication through myoendothelial gap junctions.1,2 Moncada et al3 discovered the first endotheliumderived vasoactive substance, prostacyclin, in the mid 1970s and rapidly identified its structure and chemical c...