Glutamate induces excitotoxic damage to hippocampal pyramidal neurons in Status Epilepticus (SE) and epilepsy. In this study, we investigated time course of dysregulation of calcium homeostasis at various intervals after an episode of SE in acutely isolated CA1hippocampal pyramidal. For this purpose, male Sprague-Dawley rats (200 g) were subjected to pilocarpine-induced SE. The SE was blocked a...

Objective(s): The current study was conducted to examine the possible protective and retentive effects of one-week intra-peritoneal (IP) administration of selenium nanoparticles (Se-NPs), compared to its bulk counterpart, selenite sodium (Ss), after one complete cycle of spermatogenesis in mature male mice. Materials and Methods: Thirty adult male mice were divided into 3 groups. Control group ...

The aim of present study was to investigate the potential antioxidant and lung protective activities of Sambucus ebulus (SE) against toxicity induced by gamma irradiation. Hydroalcoholic extract of SE (20, 50 and 100 mg/kg) was studied for its lung protective activity. Phenol and flavonoid contents of SE were determined. Male C57 mice were divided into ten groups with five mice per group. Only ...

selenium (se) is considered as an essential element for human body. selenized probiotic fermented milk drink (doogh) as a functional beverage to increase se available in body. the predominate sugar, protein and mineral ion of iranian yoghurt drink (doogh) are lactose, casein and calcium, respectively. different levels of  selenium (2.5 – 3- 3,5-  4 and 4.5) is prepared and its suitability based...

An experiment was conducted in order to evaluate the effects of Se spraying on yield and growth indices of wheat under drought stress condition, in agriculture and natural resource research center of Tehran province in 2011-12. A split plot layout within randomized complete block design with three replications were used. main plots were three irrigation treatments (normal irrigation, non-irriga...

Background: Endocrine compounds, such as Bisphenol A (BPA), stimulate or inhibit the activities of hormones, nuclear receptors in the central nervous system, liver and other organs. They may be disposed of in the environment inadverdently around industrial sites. The aim of this study was to evaluate the cytotoxic effects of BPA on human lymphocytes in culture at varying concentrations. Method...