subject analysis of the potential of spontaneous combustion in coal layers with analytical and numerical methods has been always considered as a difficult task because of the complexity of the coal behavior and the number of factors influencing it. empirical methods, due to accounting for certain and specific factors, have not accuracy and efficiency for all positions. the rock engineering syst...

The action of the spliceosome depends on the stepwise cooperative assembly and disassembly of its components. Very strong cooperativity was observed for the RES (Retention and Splicing) hetero-trimeric complex where the affinity from binary to tertiary interactions changes more than 100-fold and affects RNA binding. The RES complex is involved in splicing regulation and retention of not properl...

We proffer a model of computation that encompasses a broad variety of contemporary generic models, such as cellular automata—including dynamic ones, and abstract state machines— incorporating, as they do, interaction and parallelism. We ponder what it means for such an intertwined system to be effective and note that the suggested framework is ideal for representing continuous-time and asynchro...

BACKGROUND/AIM To validate prediction models for near final adult height (nFAH) by Ranke et al. [Horm Res Paediatr 2013;79:51-67]. METHODS Height data of 127 (82 male) idiopathic growth hormone (GH)-deficient children, treated with GH until nFAH, were retrieved from the database of the Belgian Society for Pediatric Endocrinology and Diabetology (BESPEED). nFAH was predicted after first-year G...