نتایج جستجو برای: reporter gene
تعداد نتایج: 1151125 فیلتر نتایج به سال:
The bait and prey fusions are co-expressed in yeast where a physical interaction between X and Y leads to the reconstitution of a functional transcription factor that binds to the promoter of a reporter gene (Fig.1). Consequently, transcription of the reporter gene is switched on. A protein-protein interaction is therefore translated into reporter gene activity which can be detected or measured...
Previously, we have reported the use of a recombinant adenovirus (Ad)-based host cell reactivation (HCR) assay to examine nucleotide excision repair (NER) of UVC-induced DNA lesions in several mammalian cell types. The recombinant non-replicating Ad expresses the Escherichia coli β-galactosidase (β-gal) reporter gene under control of the cytomegalovirus immediate-early enhancer region. We have ...
Although transgene-based reporter gene assays have been used to discover small molecules targeting expression of cancer-driving genes, the success is limited due to the fact that reporter gene expression regulated by incomplete cis-acting elements and foreign epigenetic environments does not faithfully reproduce chemical responses of endogenous genes. Here, we present an internal ribosome entry...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید