Most chronic kidney injuries inevitably progress to irreversible renal fibrosis. Tubular epithelial-to-mesenchymal transition (EMT) is recognized to play pivotal roles in the process of renal fibrosis. However, a comprehensive understanding of the pathogenesis of renal scar formation and progression remains an urgent task for renal researchers. The endogenously produced microRNAs (miRNAs), prov...

Scar endometriosis is a rare form of extra-pelvic endometriosis that can occur after surgery involving the uterus. Direct mechanical implantation seems to be the most conceivable theory for scar endometriosis. Patient usually presents with lump and pain at surgical site. Often the diagnosis of endometriosis is not suggested until histology has been performed. We hereby present a case of scar en...

cesarean scar pregnancy (csp) is a rare, but life-threatening type of ectopic pregnancy. an exact and early diagnosis of csp is very important for prognosis. the aim of the present study was to describe 4 women with csp and discuss their clinical presentations, diagnoses, and various management options along with the published literature. four women with a suspicion of csp or cervical pregnancy...

objective (s): scar formation in injured peripheral nerve bed causes several consequences which impede the process of nerve regeneration. several animal models are used for scar induction in preclinical studies which target prevention and/or suppression of perineural scar. this study evaluates the translational capacity of four of physical injury models to induce scar formation around the sciat...

Background—We report relationships between cardiovascular disease risk factors and myocardial structure, function, and scar in patients with type 1 diabetes mellitus in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. Methods and Results—Cardiac magnetic resonance was obtained in 1017 patients with type 1 diabetes mellitus....

BACKGROUND We report relationships between cardiovascular disease risk factors and myocardial structure, function, and scar in patients with type 1 diabetes mellitus in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study. METHODS AND RESULTS Cardiac magnetic resonance was obtained in 1017 patients with type 1 diabetes mellitu...

scar endometriosis is a rare form of extra-pelvic endometriosis that can occur after surgery involving the uterus. direct mechanical implantation seems to be the most conceivable theory for scar endometriosis. patient usually presents with lump and pain at surgical site. often the diagnosis of endometriosis is not suggested until histology has been performed. we hereby present a case of scar en...

BACKGROUND Coronary artery disease (CAD) patients are at risk for life-threatening ventricular arrhythmias (VA) related to scar tissue. Late gadolinium enhancement cardiovascular magnetic resonance (LGE-CMR) can accurately identify myocardial scar extent. It has been shown that scar extent, particularly scar transmurality, percent scar and scar mass, are associated with the occurrence of approp...