A young female with sickle cell disease was treated for biopsy-proven IgA nephropathy. Serum creatinine levels resolved to normal range, but a year later, she presented with oedema, hypertension and acute renal failure. A repeat renal biopsy showed acute-on-chronic thrombotic microangiopathy (TMA). We suggest that circulating microparticles could be a pathophysiological link between sickle cell...

Percutaneous renal biopsy with sonographic guidance is the standard by which renal tissue is sampled. In patients with uncorrectable coagulopathy or other contra-indication, percutaneous biopsy may not be feasible and a transvenous approach is preferred. This method limits the risk of bleeding complications as tissue is obtained endovascularly without transgression of the renal capsule. Arterio...

Renal biopsy is a crucial method in the diagnosis and treatment of acute renal failure of unknown origin, nephrotic syndrome, suspicious interstitial nephritis, and glomerulonephritis as a possible cause of hematuria or proteinuria. Complications occur in 2% to 8% of patients after percutaneous renal biopsy. Complications include gross hematuria, perirenal hematoma, arteriovenous fistula, aneur...

BACKGROUND There has been no published study of biopsy-proven childhood glomerulonephritis in Malaysia. OBJECTIVES To determine the pattern of childhood glomerulonephritis in Johor, Malaysia from a histopathological perspective and the various indications used for renal biopsy in children. MATERIALS AND METHODS Retrospective study was done of all renal biopsies from children under 16 years ...

BACKGROUND The gold standard for investigating the cause of renal graft dysfunction is renal biopsy. However, as this procedure is invasive and has inherent risks, its safety must be established. OBJECTIVE To determine the safety of percutaneous renal biopsy in pediatric orthotopic renal transplantation. METHODS Percutaneous renal biopsies performed on pediatric orthotopic renal transplants...

chronic interstitial renal disease was detected in 62.5% of the cases. Background. Children’s renal biopsy data were gathered for 3 consecutive years (1992–1994) by the Conclusions. This National Registry provides data on the indications for performing renal biopsy in Italian Group of Renal Immunopathology of the Italian Society of Pediatric Nephrology, which opened a paedichildren and on the f...

INTRODUCTION Renal biopsy is the diagnostic modality of choice for the diagnosis of renal parenchymal diseases. The advent of improved imaging techniques and biopsy needles over the years has increased the safety of the procedure and the ability to obtain adequate renal tissue for diagnosis. However, there is paucity of data in this regard from Pakistan. This study shall help in establishing th...