BACKGROUND To demonstrate and clinically, genetically and demographically characterize familial Mediterranean fever (FMF) patients, maintaining remission despite colchicine abstinence. METHODS FMF patients were screened for an endurance of prolonged remission (≥ 3 years), despite refraining from colchicine. Clinical, demographic and genetic parameters were collected. Data were compared with t...

ESSHAGH Amn,4 ARTHUR SAWITSKY,5 STANLEY LEE, STEPHAN D. MILLS, ’ E. OMER BURGERT, Jn., ’ CHARLES L. SPURR,7 RICHARD B. PATTERSON,7 FRANKLIN G. EBAUCH,5 G. \VATSON JAMES, III. AND JoHN H. MOON#{176} T 1-IE BROAD objective of the present study was to determine whether coml)inations of chemotherapeutic agents could improve the frequency and duration of complette remission in children with acute ly...

BACKGROUND The laparoscopic mini-gastric bypass is a newly emerged surgical procedure in recent years. Owe to safe and simple process and effective outcomes, laparoscopic mini-gastric bypass has quickly become one of the most popular procedures in some countries. The safety and effectiveness of laparoscopic mini-gastric bypass versus laparoscopic sleeve gastrectomy remain unclear. METHODS A s...

Kruh et al. set out to establish whether infliximab is safe and effective for the treatment of refractory noninfectious uveitis. They found that the drug—a monoclonal antibody used in treating several chronic inflammatory diseases—induced a high rate of complete clinical remission in recalcitrant uveitis and was well tolerated by most patients. In this retrospective, interventional, noncomparat...

BACKGROUND No study has investigated the impacts of migraine on depression, anxiety, and somatic symptoms and remission at the two-year follow-up point among patients with major depressive disorder (MDD). This study aimed to investigate the above issues. METHODS Psychiatric outpatients with MDD recruited at baseline were investigated at a two-year follow-up (N = 106). The Hamilton Depression ...

BACKGROUND Primary focal segmental glomerulosclerosis (FSGS) is defined by the presence of proteinuria, often in nephrotic range and pathologically by segmental scars (SS). The aim of this study is to identify the possible predictors of complete remission or progression to chronic kidney disease in Iranian adults with primary focal segmental glomerulosclerosis. METHODS In this historical coho...

Bone marrow necrosis, an uncommon finding in acute lymphoblastic leukaemia, has previously been regarded as a poor prognostic feature. It has been associated with difficulty in establishing the diagnosis, a low rate of remission as well as short remission duration. We report a case of bone marrow necrosis in a girl with acute lymphoblastic leukaemia and good prognostic features who attained com...

Background: Clinical remission is an attainable goal for Rheumatoid Arthritis (RA). However, data on RA rates in Asia-Pacific region are lacking. We conducted a cross-sectional study to evaluate the clinical status and associated factors patients region. Methods: receiving standard care were enrolled consecutively from 17 sites 11 countries. Data collected on-site by rheumatologists with sta...

BACKGROUND & AIMS We evaluated the efficacy and safety of infliximab for inducing and maintaining benefit in children with moderately to severely active ulcerative colitis (UC). METHODS Patients (6-17 years old) who had active UC (Mayo scores of 6-12; endoscopic subscores ≥ 2) and had not responded to or tolerated conventional treatment were given 5 mg/kg infliximab at weeks 0, 2, and 6. The ...