In our previous studies we have shown the potential of folate nano-carriers in releasing the encapsulated chemotherapeutic drugs at controlled rates. Also, we have seen that the release rates of encapsulated drugs and the carrier (folic acid) are comparable and can be regulated by different design parameters like particle size and cross-linking. To achieve different release rates, the design pa...

tilmicosin (tlm) is an important antibiotic in veterinary medicine with low bioavailability and safety. this study aimed to formulate and evaluate physicochemical properties, storage stability after lyophilization and antibacterial activity of three tlm-loaded lipid nanoparticles (tlm-lnps) including solid lipid nanoparticles (slns), nanostructured lipid carriers (nlcs) and lipid-core nanocapsu...

in this study, fe 3 o 4 superparamagnetic nanoparticles were synthesized and stabilized by chitosan. then the nanoparticles were characterized by fourier transform infrared spectroscopy and transmission electron microscopy (tem). particle size distribution and zeta potential of the particles also was assessed using malvern zetasizer. the paramagnetic behaviors of the uncoated and chitosan coate...

background microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. the microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. acetone/paraffin systems are conventionally used. objectives the current study aimed to investigate two diffe...