The accumulation of iron in the brain is a common physiological process. However, alterations in the deposition of iron or other paramagnetic substances are associated with various diseases. In the present study, the deposition of paramagnetic substances in patients with brain tumours was evaluated using T2 relaxometry. A total of 23 patients with untreated tumours or with recurrent tumours fol...

Longitudinal and transverse relaxation times are used to characterise the pore system of a natural Kaldenkirchen sandy loam. Here we present new results obtained by relaxometric imaging (MEMS) and two-dimensional T1-T2 correlation relaxometry, and compare these with available T1relaxation time distributions of water obtained by the analysis of fast field cycling relaxometry (FFC) data. The soil...

At low magnetic fields, T1 variation within cartilage represents a robust parameter that is employed to quantify the layered structure in the tissue and is sensitive to factors such as enzymatic degradation, external load, and diseases such as osteoarthritis. Variable-field relaxometry provides access to the quadrupolar dips that probe proton-nitrogen interaction and thus the content and local ...

Currently, a relevant proportion of all histopathologically proven focal cortical dysplasia (FCD) escape visual detection; this shows the need for additional improvements in analyzing MRI data. A positive MRI is still the strongest prognostic factor for postoperative freedom of seizures. Among several post-processing methods voxel-based morphometry (VBM) of T1- and T2-weighted sequences and T2 ...

This paper compares the physicochemical properties of six low molecular weight clinical complexes of gadolinium studied under identical experimental conditions. Magnevist, Dotarem, Omniscan, ProHance, MultiHance and Gadovist were investigated by oxygen-17 relaxometry at different temperatures and by proton relaxometry at various magnetic fields, temperatures and media [pure water, zinc(II)-cont...

The emergence of a new generation nanostructured materials opened wide range potential applications for Bioglasses such as DNA vaccination, cellular treatment or drug delivery with well-controlled loading and release (bio)active molecules. In this study we compare structural, dynamic thermal properties water confined in two CaO–SiO2–P2O5 mesoporous bioactive glasses (MBGs). One the MBGs is prep...