Racemic protein crystallography offers two key features: an increased probability of crystallization and the potential advantage of phasing centric diffraction data. In this study, a phasing strategy is developed for the scenario in which a crystal is grown from a mixture in which anomalous scattering atoms have been incorporated into only one enantiomeric form of the protein molecule in an oth...

The German banking sector is undergoing a massive transformation phase due to increasing digitalization. This challenge enormously influenced by demographic change, the low-interest phase, technological progress as well supervision and regulation. As result, banks in Germany are forced deal with strategies for customer centricity. In this context, Big Data analytics can be seen useful tool bett...

The successful integration of web2.0 applications in learning environments depends on their compatibility with the learners' objectives and requirements. Therefore, understanding the learners' view of the environment in any given scenario can facilitate this integration. In this paper we present a learner-centered strategy for integrating web2.0 applications in learning environments. This strat...

Human-centricity in manufacturing is becoming an essential enabler to achieve social sustainable manufacturing. In particular, human-centric automation can offer new means to increase competitiveness in the face of new social challenges for the factories of the future. This paper proposes a HumanCentred Reference Architecture that can structure and guide efforts to engineer Next Generation Bala...

 In this paper by use of mathematical modeling of an observer [14,15] the notion of relative information functional for relative dynamical systemson compact metric spaces is presented. We extract the information function ofan ergodic dynamical system (X,T) from the relative information of T fromthe view point of observer χX, where X denotes the base space of the system.We also generalize the in...

The scope of this paper is to introduce the research project MAGNET supported within the 6th framework of the European Commission. The project acronym MAGNET stands for “My personal Adaptive Global NET”. As the name implies, the project has a very strong emphasis on user-centricity, personalisation, adaptation, interoperability, personal networking and interconnecting heterogeneous networks. Th...

PROBLEM The healthcare system is plagued with increasing cost and poor quality outcomes. A major contributing factor for these issues is that outdated leadership practices, such as leader-centricity, linear thinking, and poor readiness for innovation, are being used in healthcare organizations. SOLUTION Complexity leadership theory provides a new framework with which healthcare leaders may pr...

In this paper, I argue that grammatical description of language is a type of information which is ideally suited to presentation as a multimedia object structured with hypertext. I examine three existing language resources, constructed for different audiences, and discuss various features of each which bear on the design issues relevant to grammatical description. From my examination of these e...

This paper describes how Department of Defense (DOD) policy groups responsible for net-centricity, interoperability, and transformation can facilitate the creation of a service bus that works for the whole enterprise instead of just within project stovepipes. Modeled after standards bodies like OASIS and open source development groups like The Apache Foundation, the approach defines an enterpri...