نتایج جستجو برای: relapses

تعداد نتایج: 5993  

Journal: :JAMA: The Journal of the American Medical Association 1918

2016
Margherita Nosadini Gulay Alper Catherine J. Riney Leslie A. Benson Shekeeb S. Mohammad Sudarshini Ramanathan Melinda Nolan Richard Appleton Richard J. Leventer Kumaran Deiva Fabienne Brilot Mark P. Gorman Amy T. Waldman Brenda Banwell Russell C. Dale

OBJECTIVE To study rituximab in pediatric neuromyelitis optica (NMO)/NMO spectrum disorders (NMOSD) and the relationship between rituximab, B cell repopulation, and relapses in order to improve rituximab monitoring and redosing. METHODS Multicenter retrospective study of 16 children with NMO/NMOSD receiving ≥2 rituximab courses. According to CD19 counts, events during rituximab were categoriz...

Journal: :Multiple sclerosis 2005
Paul O'Connor David Miller Katherine Riester Minhua Yang Michael Panzara Catherine Dalton Katherine Miszkiel Omar Khan George Rice William Sheremata

BACKGROUND Natalizumab, a humanized monoclonal IgG4 antibody, is an alpha4-integrin antagonist, which inhibits the migration of inflammatory cells into the central nervous system, a key pathogenic mechanism in multiple sclerosis (MS). In a six month, phase II clinical trial of patients with relapsing MS, natalizumab significantly reduced the formation of new gadolinium-enhanced (Gd+) lesions an...

2013
Anil Kumar Anita Girdhar B.K. Girdhar

BACKGROUND & OBJECTIVES The reported low relapse rates after 24 months multidrug therapy (MDT) for multibacillary leprosy (MB) led to the recommendation of reducing duration of therapy to 12 months. However, only a few reports exist on long term follow up data after 12 months fixed duration therapy (FDT). The present study was done to assess the incidence of relapse in MB leprosy patients after...

Journal: :The neurologist 2008
Ben W Thrower

Relapses, exacerbations, and attacks are synonymous for new or worsened neurologic symptoms that are the hallmark of relapsing-remitting multiple sclerosis. Management of relapses is not always straightforward. The clinician must distinguish between true relapses, symptom fluctuation, and pseudo-relapses. Risks and benefits of treating a relapse must be considered. Once the decision to treat is...

Journal: :iranian journal of neurology 0
masoud nikanfar department of neurology, neuroscience research center, imam reza hospital, tabriz university of medical sciences, tabriz, iran. ali akbar taheri-aghdam department of neurology, neuroscience research center, imam reza hospital, tabriz university of medical sciences, tabriz, iran. maria yazdani department of neurology, neuroscience research center, imam reza hospital, tabriz university of medical sciences, tabriz, iran. sheida shaafi department of neurology, neuroscience research center, imam reza hospital, tabriz university of medical sciences, tabriz, iran. nooshin masoudian department of neurology, school of medicine, tabriz university of medical sciences, tabriz, iran. hossein akbari department of neurology, school of medicine, tabriz university of medical sciences, tabriz, iran.

background: it seems that serum vitamin d levels are one of the potential environmental factors affecting the severity of multiple sclerosis (ms). in this study, we aim to evaluate vitamin d levels in ms patients and healthy subjects and assess the relationship between vitamin d level and disability. methods: in this case-control study, 168 rapid relapsing ms patients and 168 matched healthy co...

Journal: :Nephrology Dialysis Transplantation 2015

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