Diabetes and cancer are common conditions, and their co-diagnosis in the same individual is not infrequent. A link between the two conditions has been postulated for almost 80 years, but only in the past decade has significant epidemiological evidence been amassed to suggest that diabetes and cancer are associated, and the link appears causal. Hyperinsulinaemia, adipocytokines, growth factors a...

comparing the islamic logic and jurisprudential principles, and basedon the separation between minor and major authorities (hujjiyyatsughrawi wa kubrawi), it can be proved that (1) minor authority ofsuitable verbal text per nexum (al-mantuq al-muwafiq al-iltizami),minor authority of suitable concept per nexum (al-mafhum al-muwafiqal-iltizami), and minor authority of contrary concept (al-mafhum ...

Pulmonary hypertension is a prevalent complication of chronic obstructive pulmonary disease (COPD) that is associated with poor prognosis. Although pulmonary hypertension is usually diagnosed in patients with advanced disease, changes in pulmonary vessels are already apparent at early disease stages, and in smokers without airflow obstruction. Changes in pulmonary vessels include intimal hyperp...

Only indirect or circumstantial evidence has been published to support transmission of Rickettsia rickettsii by Amblyomma americanum (lone star) ticks in North America. This study provides molecular evidence that A. americanum ticks can function, although most likely infrequently, as vectors of Rocky Mountain spotted fever for humans.

There is considerable circumstantial evidence that the Ca(2+)-mobilizing second messenger IP(3) is involved in plant responses to the drought hormone abscisic acid. More direct evidence for this has now come from studies in which endogenous IP(3) levels have been manipulated in plants.

Background: Male reproductive disorders that are of interest from an environmental point of view include sexual dysfunction, infertility, cryptorchidism, hypospadias and testicular cancer. Several reports suggest declining sperm counts and increase of these reproductive disorders in some areas during some time periods past 50 years. Materials and Methods: Except for testicular cancer this evide...

This paper provides experimental evidence from German and English against the view that a goal to/zu-PP in combination with motion verb designates is reached. We propose to/zu have modal meaning, responsible for defeasibility of inference argue type subjects (intentional agent vs. accidental or theme) determines flavor (necessity) encoded by preposition (teleological circumstantial), which allo...

According to amuch discussed argument, reliabilism is defective formaking knowledge too easy to come by. In a recent paper, Weisberg aims to show that this argument relies on a type of reasoning that is rejectable on independent grounds. We argue that the blanket rejection that Weisberg recommends of this type of reasoning is both unwarranted and unwelcome. Drawing on an older discussion in the...