The relative sensitivity and specificity of individual and combined noninvasive tests to detect coronary heart disease were evaluated in 75 patients with chest pain admitted for cardiac catheterization and coronary arteriography. Of the 75 patients, 56 had coronary heart disease. Exercise-induced ST-segment abnormalities (>1 mm) were found in 58%. In contrast, computer-processed exercise thalli...

BACKGROUND The incremental value of regional left ventricular function (LVF) over coronary assessment to detect acute coronary syndrome (ACS) is uncertain. METHODS AND RESULTS We analyzed 356 patients (mean age, 53+/-12 years; 62% men) with acute chest pain and inconclusive initial emergency department evaluation. Patients underwent 64-slice contrast-enhanced cardiac computed tomography befor...

BACKGROUND Tissue tagging by cardiovascular magnetic resonance (CMR) is a comprehensive method for the assessment of cardiac regional function. However, imaging the right ventricle (RV) using this technique is problematic due to the thin wall of the RV relative to tag spacing which limits assessment of regional function using conventional in-plane tagging. HYPOTHESIS We hypothesize that the u...

BACKGROUND Regional myocardial function assessment is essential in the management of coronary artery disease (CAD). Tissue Doppler imaging (TDI) by depicting local myocardial motion can potentially quantify regional myocardial function. Strain rate imaging (SRI) that depicts regional deformation is less susceptible to cardiac translation and tethering and may be superior to TDI for regional fun...

Perfusion assessment during cardiopulmonary bypass can be stratified into global and regional categories. This discussion will cover global assessment and selected regional assessments. Ingoing assumptions for this discussion are: 1. Heart and lung perfusion are “out of the loop” during CPB 2. The oxygenator is delivering adequate O2 and removing adequate CO2 3. Hemoglobin concentration is suff...

This paper discusses some key points related to the ontology of the “appropriate assessment” [1] procedure concerning plans significantly affecting Natura 2000 sites. We study this ontology by discussing its implementation into the adjustment process of the master plans of the regional municipalities of Sardinia (Italy) to the Regional Landscape Plan (RLP) and put as evidence some important gen...

AIMS Transthoracic murine echocardiography is a cornerstone of small animal research, but conventional methods cannot detect regional perturbations in cardiac function. Reliable assessment of regional cardiac function would be of value in transgenic models of myocardial disease. Until now automatized algorithms for achieving this suffers from a number of drawbacks. We developed a simple algorit...

OBJECTIVES To determine the potential utility of the frontal assessment battery (FAB) in assessing cognitive impairments in amyotrophic lateral sclerosis (ALS), we investigated the association between the FAB score and regional gray matter volume, and ascertained whether the regional brain alterations related to cognitive impairments occur in relatively mild stage of ALS. MATERIALS AND METHOD...