نتایج جستجو برای: rectal toxicity imrt

تعداد نتایج: 151115  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Eva Christensen Melania Pintilie Kenneth R Evans Michelle Lenarduzzi Cynthia Ménard Charles N Catton Eleftherios P Diamandis Robert G Bristow

PURPOSE Proteomic profiling of patients undergoing intensity-modulated radiotherapy (IMRT) for prostate cancer can identify unique biomarkers that reflect acute toxicity in normal tissues. Our objectives were to measure inflammatory cytokine proteins during IMRT and assess the variability of individual proteomic signatures. EXPERIMENTAL DESIGN Forty-two patients with intermediate-risk prostat...

2014
Ji Zhu Fangqi Liu Weilie Gu Peng Lian Weiqi Sheng Junyan Xu Gang Cai Debing Shi Sanjun Cai Zhen Zhang

AIM This study was designed to evaluate the efficacy and toxicities of concomitant boost intensity-modulated radiation therapy (IMRT) along with capecitabine and oxaliplatin, followed by a cycle of Xelox, in neoadjuvant course for locally advanced rectal cancer. MATERIALS AND METHODS Patients with histologically confirmed, newly diagnosed, locally advanced rectal adenocarcinoma (cT3-T4 and/or...

Journal: :International journal of radiation oncology, biology, physics 2017
Arunan Sujenthiran Julie Nossiter Susan C Charman Matthew Parry Prokar Dasgupta Jan van der Meulen Paul J Cathcart Noel W Clarke Heather Payne Ajay Aggarwal

PURPOSE To compare, in a national population-based study, severe genitourinary (GU) and gastrointestinal (GI) toxicity in patients with prostate cancer who were treated with radical intensity modulated radiation therapy (IMRT) or 3-dimensional conformal radiation therapy (3D-CRT). METHODS AND MATERIALS Patients treated with IMRT (n=6933) or 3D-CRT (n=16,289) between January 1, 2010 and Decemb...

Journal: :The Laryngoscope 2013
Abrahim Al-Mamgani Peter van Rooij Gerda M Verduijn Robert Mehilal Jeroen D Kerrebijn Peter C Levendag

OBJECTIVES/HYPOTHESIS To investigate the impact of treatment modality and radiation technique on oncologic outcomes and toxicity of patients with locally advanced oropharyngeal cancer (OPC). STUDY DESIGN Retrospective analysis of outcomes and toxicity. METHODS Between 2000 and 2011, 204 consecutive patients with locally advanced OPC were treated with definitive (chemo)radiotherapy using 3-d...

Journal: :Journal of medical imaging and radiation oncology 2017
Stephen Chin Noel J Aherne Andrew Last Hassan Assareh Thomas P Shakespeare

INTRODUCTION We evaluated single institution toxicity outcomes after post-prostatectomy radiotherapy (PPRT) via image-guided intensity-modulated radiation therapy (IG-IMRT) with implanted fiducial markers following national eviQ guidelines, for which late toxicity outcomes have not been published. METHODS Prospectively collected toxicity data were retrospectively reviewed for 293 men who unde...

2011
Matthias Uhl Klaus Herfarth Danny Song

Study Objective. To evaluate the space creation, maintenance and absorption of an absorbable hydrogel injected into the perirectal space of patients prior to undergoing prostate radiotherapy. Design. CT or MR imaging performed before hydrogel application (Baseline), one week after hydrogel application, following 8 weeks of IMRT (78Gy total) and then again 6 months following implantation. Settin...

2013
Connor Chevli Ramkishen Narayanan Lisa Rambarran Gregory Kubicek K Kent Chevli Michael Duff

BACKGROUND The aim of this study was to describe the effect of pretreatment prostate volume on urinary quality of life after intensity-modulated radiation therapy (IMRT) for clinically localized prostate cancer. METHODS A total of 368 men treated with prostate IMRT (77.4-81 Gy) were stratified into three gland volume groups, ie, <30 g (group 1), 30-60 g (group 2), and >60 g (group 3). Post-IM...

2017
Milly Buwenge Silvia Cammelli Ilario Ammendolia Giorgio Tolento Alice Zamagni Alessandra Arcelli Gabriella Macchia Francesco Deodato Savino Cilla Alessio G Morganti

BACKGROUND Owing to highly conformed dose distribution, intensity modulated radiation therapy (IMRT) has the potential to improve treatment results of radiotherapy (RT). Postoperative RT is a standard adjuvant treatment in conservative treatment of breast cancer (BC). The aim of this review is to analyze available evidence from randomized controlled trials (RCTs) on IMRT in BC, particularly in ...

2017
Xin-Bin Pan Kai-Hua Chen Shi-Ting Huang Yan-Ming Jiang Jia-Lin Ma Zhong-Guo Liang Song Qu Ling Li Long Chen Xiao-Dong Zhu

We compared treatment outcomes in patients with stage II nasopharyngeal carcinoma (NPC) treated with intensity-modulated radiotherapy (IMRT) or two-dimensional conventional radiotherapy (2D-CRT). Stage II (2010 UICC/AJCC staging system) NPC patients treated with IMRT (n = 178) or 2D-CRT (n = 73) between January 2007 and December 2014 were retrospectively analyzed. Patients were matched using th...

2013
Hua Yang Li-Qiong Diao Mei Shi Rui Ma Jian-Hua Wang Jian-Ping Li Feng Xiao Ying Xue Man Xu Bin Zhou

OBJECTIVES Long-term locoregional control following intensity-modulated radiotherapy (IMRT) for locally advanced squamous cell carcinoma of the head-and-neck (SCCHN) remains challenging. This study aimed to assess the efficacy and toxicity of IMRT with and without chemotherapy or surgery in locally advanced SCCHN. MATERIALS AND METHODS Between January 2007 and January 2011, 61 patients with l...

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