نتایج جستجو برای: recombinant tissue plasminogen activator

تعداد نتایج: 1042779  

Journal: :Stroke 1992
Y Okada S Sadoshima H Nakane H Utsunomiya M Fujishima

BACKGROUND AND PURPOSE The benefits and safety of thrombolytic therapy was studied in patients with acute brain embolism. METHODS We intravenously administered recombinant tissue plasminogen activator (20-30 MU for 1 hour) to 10 patients with acute (less than 6 hours) brain embolism and examined the neurological outcomes in relation to the findings on computed tomography and angiography. RE...

Journal: :research in pharmaceutical sciences 0
h mir mohammad sadeghi m rabbani e rismani f moazen f khodabakhsh k dormiani

reteplase is a segment of tissue plasminogen activator used for the removal of thrombi in blood vessels. in the present study the cloned reteplase gene was used for its expression in competent e. coli. the  recombinant plasmid, pet15b/reteplase (rpet-bl21), was transformed into competent e.coli strain bl21 (de3) cells. overnight culture of the transformed bacteria was induced by the addition of...

Journal: :Stroke 2015
Richard I Lindley Joanna M Wardlaw William N Whiteley Geoff Cohen Lisa Blackwell Gordon D Murray Peter A G Sandercock

BACKGROUND AND PURPOSE Our aim was to identify whether particular subgroups of patients had an unacceptably high risk of symptomatic intracranial hemorrhage or low chance of benefit when treated with alteplase (recombinant tissue-type plasminogen activator). METHODS Third International Stroke Trial was an international randomized trial of the intravenous (IV) recombinant plasminogen activator...

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