نتایج جستجو برای: recombinant reteplase
تعداد نتایج: 111111 فیلتر نتایج به سال:
BACKGROUND New recombinant plasminogen activators have been developed to simulate the fibrinolytic action of the physiological serine protease tissue plasminogen activator (alteplase, t-PA), and have prolonged half-life features permitting bolus administration. One such activator, reteplase (r-PA), was compared with t-PA in the Global Utilization of Streptokinase and t-PA for Occluded Coronary ...
A 61year old man on chronic aspirin treatment with unstable angina was admitted to our hospital to undergo programmed percutaneous coronary artery angioplasty. A balloon angioplasty (with a 3.5 mm diameter balloon) to a type B lesion in the proximal LAD was performed, and a stent (4.0 x 16mm stent) was implanted because of a dissection producing acute vessel occlusion. During the procedure 5000...
OBJECTIVES This study was undertaken to assess prospectively the prognostic power of early ST segment elevation resolution in a large cohort of patients with myocardial infarction and to test the value of differences in ST segment resolution as a surrogate end point. BACKGROUND Previous studies revealed that the use of two cutoff points for three groups of ST segment resolution within 3 h aft...
results the results showed that sensitivity and specificity were respectively 84.12% and 92% for recombinant protein srs3 and 92% and 96% for rsag1. conclusions recombinant proteins srs3 and rsag1 are promising antigens in diagnostic assays for detection of specific antibodies against t. gondii. background infections by the protozoan parasite toxoplasma gondii (t. gondii) are widely prevalent ...
BACKGROUND Long-term central venous catheters have improved the quality of care for patients with chronic illnesses, but are complicated by obstructions which can result in delay of treatment or catheter removal. DESIGN AND METHODS This paper reviews thrombolytic treatment for catheter obstruction. Literature from Medline searches using the terms "central venous catheter", "central venous acc...
Reteplase (rPA) is a thrombolytic agent used for the treatment of acute myocardial infarction. We studied the expression of rPA and its selected asparagine mutants after integration into the Pichia genome. Though methanol induction of the native and the rPA mutants showed similar expression levels (~200-250 mg/L), the mutants displayed significant loss of protease activity. Strikingly, the clot...
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