Precise readout of spin states is crucial for any approach toward physical realization of a spin-based quantum computer and for magnetometry with single spins. Here, we report a method to strongly improve the optical readout fidelity of electron spin states associated with single nitrogen-vacancy NV centers in diamond. The signal-to-noise ratio is enhanced significantly by performing conditiona...

A prepolarized MRI (PMRI) scanner was used to image near metal implants in agar gel phantoms and in in vivo human wrists. Comparison images were made on 1.5- and 0.5-T conventional whole-body systems. The PMRI experiments were performed in a smaller bore system tailored to extremity imaging with a prepolarization magnetic field of 0.4 T and a readout magnetic field of 27-54 mT (1.1-2.2 MHz). Sc...

The use of small interfering RNA molecules for therapeutic applications requires development of improved delivery systems, a process that would be facilitated by a non-invasive positive-readout mouse model for studying siRNA pharmacodynamics. Positive readout would yield better signal/noise ratios than existing negative-readout systems. We have engineered a positive-readout luciferase reporter ...

The OPAL experiment at the CERN LEP collider recently upgraded its silicon strip microvertex detector from one coordinate readout ( only) to two coordinate readout ( and z). This allows three dimensional vertex reconstruction and should improve lifetime measurements as well as b quark jet identi cation. This paper describes the new microvertex detector system with emphasis on the novel techniqu...

Superconducting quantum bits (qubits) are promising candidates for scalable, fault-tolerant quantum computation. Being able to determine a quantum state with a single measurement is essential for using any quantum system for computation. In this thesis single shot readout is implemented for hybrid semiconductor based superconducting qubits by integrating a near quantum limited parametric amplif...

We have developed and successfully demonstrated a high speed, low noise camera system for crystallography and X-ray imaging applications. By coupling an EM-CCD to a 3:1 fibre optic taper and a CsI(Tl) scintillator it was possible to detect hard X-rays. This novel approach to hard X-ray imaging takes advantage of the low equivalent readout noise performance at high pixel readout frequencies of E...

We present initial results on the comparison of the dose readout from a three dimensional polymer gel dosimeter using two different optical-CT systems; i) a common wide field and a wide area detector optical-CT system and ii) a new ‘laser-line’ and wide area detector based optical-CT system. The findings presented herein highlight the advantage of the laser based over the wide field optical-CT ...

Conventional readout systems exist in many variants since the usual approach is to build readout electronics for one given type of detector. The Scalable Readout System (SRS) developed within the RD51 collaboration relaxes this situation considerably by providing a choice of frontends which are connected over a customizable interface to a common SRS DAQ architecture. This allows sharing develop...

We report initial results from the design and evaluation of two pixellated PIN Cadmium Zinc Telluride detectors and an ASIC-based readout system. The prototype imaging PIN detectors consist of 4 × 4 1.5 mm square indium anode contacts with 0.2 mm spacing and a solid cathode plane on 10 × 10 mm CdZnTe substrates of thickness 2 mm and 5 mm. The detector readout system, based on low noise preampli...

Abstract We present an FPGA-based readout chip emulator board for the CMS Endcap Timing Layer (ETL) detector upgrade. The uses Intel Cyclone 10 GX FPGA to emulate digital functions of four Readout Chips (ETROCs). Based on actual ETROC design, firmware is implemented and verified. being used design verification system development.