Randomized controlled trials (RCT) are the optimal study design to answer intervention questions. The authors evaluated the number, quality, and coverage of RCT in nephrology. MEDLINE was searched using the relevant medical subject headings for nephrology and 12 major specialties in internal medicine, limited by "randomized controlled trial" as a publication type. A random selection of 160 RCT ...

INTRODUCTION This cross-sectional survey determined the dental prevalence of apical periodontitis (AP) in selected Iranian population, and evaluated the influence of the quality of root canal treatment (RCT) and their coronal restorations (CR) on the periapical status. MATERIALS AND METHODS A total of 1064 panoramic radiographies were evaluated by two observers during 2009. The quality of RCT...

BACKGROUND Preoperative radiochemotherapy (RCT) is standard in locally advanced rectal cancer (LARC). Initial data suggest that the tumor's metabolic response, i.e. reduction of its 18 F-FDG uptake compared with the baseline, observed after two weeks of RCT, may correlate with histopathological response. This prospective study evaluated the ability of a very early metabolic response, seen after...

BACKGROUND Sexually transmitted infections (STIs) are more common in young people and men who have sex with men (MSM) and effective in-service interventions are needed. METHODS A systematic review of randomized controlled trials (RCTs) of waiting-room-delivered, self-delivered and brief healthcare-provider-delivered interventions designed to reduce STIs, increase use of home-based STI testing...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Nadeem K, Arif M, Akram S, Arslan SA, Ahmad A, Gilani SA. Effect of IASTM ergon technique on pain, strength and range motion in plantar fasciitis patients. RCT. Physiotherapy Quarterly. 2023. doi:10.5114/pq.2023.125109. APA Nadeem, K., Arif, M., Akram, S., Arslan, S. A., Ahmad, & Gilani, A. (2023). https://doi.org...

Qualitative methods seek to answer different questions from those of RCT, and for those types of questions they potentially provide a high level of evidence, higher than that of the RCT. “Potentially” remains an important qualification since as with any research the level of evidence produced is also dependent on the rigour of the study itself. Just as a poorly designed or conducted RCT provide...

BACKGROUND The effectiveness of an intervention in clinical practice is often reduced compared to the efficacy demonstrated in a randomised controlled trial (RCT). In this comparative effectiveness study, the RCT-proven efficacy of a diabetes education programme for type 1 diabetic patients (PRIMAS) was compared to the effectiveness observed in an implementation trial (IT) under routine care co...

This review considers the antiatherogenic function of high density lipoprotein (HDL) from the point of view of its dynamics within the sequential steps of reverse cholesterol transport (RCT). It is postulated that the efficiency of cholesterol flux through the RCT pathways is clinically more relevant than the HDL cholesterol concentration. The particular role of pre-beta(1)-HDL is reviewed draw...

AIM Peripheral arterial disease (PAD), particularly critical limb ischemia (CLI), is a severe cause of amputation and mortality. More than 50% of diabetic patients with CLI die within four to five years. The development of novel stem cell therapies may bring new hope to these patients. We aimed to assess the efficacy of autologous bone marrow cell therapy for treating CLI using a meta-analysis....

to identify the antidiabetic plants of iran, a systematic review of the published literature on the efficacy of iranian medicinal plant for glucose control in patients with type 2 diabetes mellitus was conducted. we performed an electronic literature search of medline, science direct, scopus, proquest, ebsco, googlescholar, sid, cochrane library database, from 1966 up to june 2010. the search t...