نتایج جستجو برای: rat heart
تعداد نتایج: 648004 فیلتر نتایج به سال:
Oxygen-induced regulation of Na,K-ATPase was studied in rat myocardium. In rat heart, Na,K-ATPase responded to hypoxia with a dose-dependent inhibition in hydrolytic activity. Inhibition of Na,K-ATPase in hypoxic rat heart was associated with decrease in nitric oxide (NO) production and progressive oxidative stress. Accumulation of oxidized glutathione (GSSG) and decrease in NO availability in ...
The citrate synthases from rat heart and rat liver have been purified. These homogeneous proteins have a molecular weight of about 1 x lo5 and are composed of 2 apparently identical subunits. Kinetic constants for acetyl coenzyme A and oxaloacetate and the Ki for ATP are the same for both enzymes. Immunological studies using antibody to the rat heart enzyme also indicate that the enzymes are id...
Mechanical unloading of the rat heart increases both protein synthesis and protein degradation. The transcriptional mechanism underlying increased protein synthesis during atrophic remodeling is not known. The aim of this study was to identify transcriptional regulators and the gene expression profile regulating protein synthesis in the unloaded rat heart and in the unloaded failing human heart...
Tissue-engineered grafts may be useful in myocardial repair; however, previous scaffolds have been structurally incompatible with recapitulating cardiac anisotropy. Here, we use microfabrication techniques to create an accordion-like honeycomb microstructure in poly(glycerol sebacate), which yields porous, elastomeric three-dimensional (3D) scaffolds with controllable stiffness and anisotropy. ...
Background: Diabetes mellitus in pregnancy can cause heart histological changes. This study was done to evaluate the effect of barly grain (Hordeum Vulgar L.) consumption during pregnancy in diabetic rats on heart histological altrations of offsprings. Methods: In this experimental study ,60 adult female albino rats, randomly allocated into four groups including: healthy group with regul...
Mucuna pruriens is widely used in traditional medicine for treatments of various diseases. In certain region of Nigeria, the seed is used as oral prophylactics for snakebite. Rats pretreated with the aqueous extract from M. pruriens seed (MPE) were protected against the lethal effects of Naja sputatrix (Javan spitting cobra) venom [Tan et al., J Ethnopharmacol, 123 (2009) 356]. The pretreatment...
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