Using an explant culture system, we have demonstrated that human somatotropes respond to growth hormone releasing factor (GRF) and somatostatin (SRIF) from as early as 9.5 weeks of fetal age. Responsiveness to GRF increases significantly as a function of age up to midgestation while SRIF inhibition of basal growth hormone (GH) release does not change. SRIF has little effect on GRF-stimulated GH...

GH-releasing factor (GRF) is the hypothalamic peptide that stimulates both synthesis and secretion of GH. The GRF signal is transduced to somatotroph cells through pituitary GRF receptors and generates episodic bursts of GH secretion into the bloodstream. Secretion of GH is highly sexually dimorphic, particularly in the rat [1]. In female rats, GH surges are of lower amplitude and occur more ir...

Let E be an ideal of Lo over a σ-finite measure space (Ω,Σ, μ), and let (X, ‖ ·‖X) be a real Banach space. Let E(X) be a subspace of the space Lo(X) of μ-equivalence classes of all strongly Σ-measurable functions f : Ω −→ X and consisting of all those f ∈ Lo(X) for which the scalar function ‖f(·)‖X belongs to E. Let E(X)n stand for the order continuous dual of E(X). In this paper we characteriz...

Abstract We show how to build a kernel $$ K_X(x,y)=\sum _{m=0}^Xh(\lambda _m/{\lambda _X})\varphi _m(x)\overline{\varphi _m(y)} K X ( x , y ) = ...

Data summarization is an effective approach to dealing with the “big data” problem. Whiledata summarization problems traditionally have been studied is the streaming model, the focus isstarting to shift to distributed models, as distributed/parallel computation seems to be the only viableway to handle today’s massive data sets. In this paper, we study ε-approximations, a classic...

A Tychonoff space X is called RG if the embedding of C(X) → C(Xδ) is an epimorphism of rings. Compact RG spaces are known and easily described. We study the pseudocompact RG spaces. These must be scattered of finite Cantor Bendixon degree but need not be locally compact. However, under strong hypotheses, (countable compactness, or small cardinality) these spaces must, indeed, be compact. The ma...

‎by considering a degenerate $p(x)-$laplacian equation‎, ‎a generalized compact embedding in weighted variable‎ ‎exponent sobolev space is presented‎. ‎multiplicity of positive solutions are discussed by applying fibering map approach for the‎ ‎corresponding nehari manifold‎.