نتایج جستجو برای: randomised trials
تعداد نتایج: 241507 فیلتر نتایج به سال:
Reports of cluster randomised trials require additional information to allow readers to interpret them accurately The effective reporting of randomised controlled trials has received useful attention in recent years. Many journals now require that reports conform to the guidelines in the Consolidated Standards of Reporting Trials (CONSORT) statement, first published in 1996 and revised in 2001....
OBJECTIVES To determine whether an association exists between the number of published randomised controlled trials and the global burden of disease, whether certain diseases are under-investigated relative to their burden, and whether the relation between the output of randomised trials and global burden of disease can be explained by the relative disease burden in high and low income regions. ...
This paper summarises the arguments and counterarguments within scientific discussion on cash transfers child nutrition. The main purpose of research is to assess effectiveness in improving nutritional outcomes vulnerable children sub-Saharan Africa. Systematisation literary sources indicates that studies have justified transfer as social-income support addresses a vital social determinant heal...
BACKGROUND Randomised controlled trials can provide evidence relevant to assessing the equity impact of an intervention, but such information is often poorly reported. We describe a conceptual framework to identify health equity-relevant randomised trials with the aim of improving the design and reporting of such trials. METHODS An interdisciplinary and international research team engaged in ...
BACKGROUND Poor recruitment to randomised controlled trials (RCTs) is a widespread and important problem. With poor recruitment being such an important issue with respect to the conduct of randomised trials, a systematic review of controlled trials on recruitment methods was undertaken in order to identify strategies that are effective. METHODS We searched the register of trials in Cochrane l...
OBJECTIVE To assess if authors of randomised clinical trials convey the fact that they have used surrogate outcomes and discussed their validity. DESIGN Cohort study. SETTING Six major general medical journals. PARTICIPANTS Randomised clinical trials published in 2005 and 2006 that used a surrogate as a primary outcome. RESULTS Of 626 published randomised clinical trials, 109 (17%) used...
BACKGROUND Randomised control trials are regarded as the gold standard for evaluating the effectiveness and efficacy of healthcare interventions with thousands of trials published every year. Despite significant investment in infrastructure, a staggering number of clinical trials continue to face challenges with retention. Dropouts could lead to negative consequences-from lengthy delays to miss...
OBJECTIVE To conduct a systematic review of the efficacy and safety of exogenous melatonin in managing secondary sleep disorders and sleep disorders accompanying sleep restriction, such as jet lag and shiftwork disorder. DATA SOURCES 13 electronic databases and reference lists of relevant reviews and included studies; Associated Professional Sleep Society abstracts (1999 to 2003). STUDY SEL...
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