Descriptions of the weight of a tumor and the magnitude of its blood flow have been of interest for a number of years. Despite this, there have been no reported attempts to provide quantitative relationships between the tumor's weight and its rate of perfusion. An initial approach to such a relationship, which adequately describes all known data in the literature thus far, is given in the prese...

HE feasibility of surgical relief of hypertensioni associated with renal arterv stenosis has been clearly established.'-` In the -preoperative diagnosis of seconidary hyperten sioni of this type, funietioni studies anid arteriogoraphy have been the oinlv available procedures. However, 7renal arteriography and studies of separated renal functions after eystoscopic examination and bilateral urete...

BACKGROUND Scientific approach of the bone reaction after surgical procedures provides valuable information on methods and techniques. The purpose of this study was to follow this process using a radioisotope marker of bone remodelling. MATERIAL AND METHODS Two bone cavities were created (one for every tibia) in adult Wistar male rats using a 0.5 mm spherical burr; left tibial cavities were f...

Of 89 patients admitted to coronary care after myocardial infarction, 27 per cent developed radioisotopic evidence of deep venous thrombosis. This complication occurred more frequently if the patient was over 6o years, if there was a previous history of angina pectoris, and if heart failure or a significant dysrhythmia developed. A group of patients with a low incidence of deep venous thrombosi...

We demonstrate a general approach for metabolic engineering of biocatalytic systems comprising the uses of a chemostat for strain improvement and radioisotopic tracers for the quantification of pathway fluxes. Flux determination allows the identification of target pathways for modification as validated by subsequent overexpression of the corresponding gene. We demonstrate this method in the ind...

radioisotopic (Daly, 1972; McIlwain, 1974) studies. Thus the post-stimulation increase in synaptosomal cyclic AMP can most readily be seen as migration of the nucleotide, by intracellular or extracellular routes, from those localized sites, although there is also a possibility of adenosine as intermediate. Independently of route, the delayed increase in nerve-terminal cyclic AMP is significant ...

A commercial kit for the radioisotopic assay of folate in serum, the Bio-Rad 'Quanta Count' folate kit, produced lower results than the Lactobacillus casei microbiological assay method. Its normal range was 2-0-13-0 microng/l and the reproducibility was similar to that of the microbiological assay method. The kit was also satisfactory for whole bood folate assays. The cost requires careful cons...