Introduction: A low iodine diet (LID) is recommended prior to the Radioactive Iodine-131 (RAI) treatment or scanning in differentiated thyroid carcinoma (DTC) post total thyroidectomy. However, recommended strictness of LID is varying among major guidelines. This study was aim to investigate the patient’s compliance to LID by measuring the urinary iodine level post LID. <...

OBJECTIVE To characterize the phenotype of patients with congenital hypothyroidism (CH) due to dyshormonogenesis, and to hypothesize on the degree of genetic defect. SUBJECTS AND METHODS Patients with dyshormonogenesis were subdivided into G1 (radioactive iodine uptake, RAIU > 15%; n = 62) and G2 (RAIU < 15%; n = 32). Thyroglobulin (TG) was measured in all patients; perchlorate discharge test...

Purpose Calculation of effective thyroidal half-life (Teff) of iodine-131(131I) is cumbersome and tedious. The aim of this study was to investigate factors that could be used to predict Teff and to develop a Teff prediction model in Graves' disease patients. Methods A total of 256 patients with GD were involved in this study. We investigated the influences of age, gender, disease duration, th...

Standby Gas Treatment System (SGTS) is one of the engineered safety features installed in BWR and ABWR plants to limit the discharge of radioactivity into the environment during the reactor accident. Kl3 impregnated charcoal (iodized charcoal) filter is used for removing of radioactive iodine species such as molecular iodine and methyl iodide. It is well known that the removal capability of imp...

A patient presented with hyperthyroidism and end-stage renal disease requiring hemodialysis that was difficult to control despite increased dosages of anti-thyroid drugs. The condition could finally be controlled by 131I radioactive iodine therapy (RIT) and hemodialysis provided under a hospital-linkage system. During three hemodialysis sessions after the oral administration of 131I, we measure...

The case records of 262 patients who received 131I therapy during a 6-year period were analysed retrospectively. These included seventy-eight patients who received more than one therapeutic dose. The major indication for 131I therapy was thyrotoxicosis occurring in patients aged 40 years and over. The racial incidence in this series is striking. The effects on thyroid function of two low-dose s...

I . Iodine metabolism was studied using labelled sodium iodide in subjects with endemic goitre which is prevalent in the south-west part of Ceylon, where the iodine content of the drinking water was shown to be low. The study was confined mostly to children of school age. 2. The patients showed raised thyroidal uptake of lS1I and 48 h serum protein-bound radioactive iodine, lowered plasma inorg...

Over the last decades, treatment of Graves’ disease has been limited to antithyroid drugs, radioactive iodine ablation or surgery. Especially in paediatric age group, all three therapeutic options have their advantages and side effects.

Introduction: High-dose radioactive iodine therapy in differentiated thyroid cancer (DTC) may adversely affect the salivary gland function. This study is aimed to evaluate the effect of radioactive iodine (RAI) with dose of 100 mCi in DTC patients compared to lower doses of less than 30 mCi in hyperthyroid cases. Methods: Fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...

Radioiodinated meta-iodobenzylguanidine (MIBG) is one of the important radiopharmaceuticals in Nuclear Medicine. [(123/131)I] MIBG is used for imaging of Adrenal medulla, studying heart sympathetic nerves, treatment of pheochromacytoma and neuroblastoma. For clinical application, radioiodinated MIBG is prepared through isotopic exchange method, which includes replacement of radioactive iodine i...